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Disabled man slams Qantas after they damaged his wheelchair

<p>An Australian man has called out Qantas for damaging his wheelchair during a flight, and then offering him a slim compensation package that wouldn't cover the cost of the repair. </p> <p>Queensland wheelchair athlete Timothy Lachlan was travelling from the USA to Sydney when he claims Qantas luggage handlers broke his wheelchair as it was being loaded onto the plane. </p> <p>Like many Australians living with a disability, Lachlan described his wheelchair as "his legs".</p> <p>"This wheelchair is basically my legs — Qantas has basically broken my legs," he told <em>7News</em> of the custom chair he's owned for more than a decade.</p> <p>"If you go up the slightest incline, the chair just tips back."</p> <p>Lachlan now can no longer use the chair and says the saga has cost him work as an occupational therapist. He's currently borrowing a friend's chair to get around and says though he did try to fix his chair, he wasn't able due to the extent of the damage.</p> <blockquote class="instagram-media" style="background: #FFF; border: 0; border-radius: 3px; box-shadow: 0 0 1px 0 rgba(0,0,0,0.5),0 1px 10px 0 rgba(0,0,0,0.15); margin: 1px; max-width: 540px; min-width: 326px; padding: 0; width: calc(100% - 2px);" data-instgrm-permalink="https://www.instagram.com/reel/C7Q68PmJYXV/?utm_source=ig_embed&utm_campaign=loading" data-instgrm-version="14"> <div style="padding: 16px;"> <div style="display: flex; flex-direction: row; align-items: center;"> <div style="background-color: #f4f4f4; border-radius: 50%; flex-grow: 0; height: 40px; margin-right: 14px; width: 40px;"> </div> <div style="display: flex; flex-direction: column; flex-grow: 1; justify-content: center;"> <div style="background-color: #f4f4f4; border-radius: 4px; flex-grow: 0; height: 14px; margin-bottom: 6px; width: 100px;"> </div> <div style="background-color: #f4f4f4; border-radius: 4px; flex-grow: 0; height: 14px; width: 60px;"> </div> </div> </div> <div style="padding: 19% 0;"> </div> <div style="display: block; height: 50px; margin: 0 auto 12px; width: 50px;"> </div> <div style="padding-top: 8px;"> <div style="color: #3897f0; font-family: Arial,sans-serif; font-size: 14px; font-style: normal; font-weight: 550; line-height: 18px;">View this post on Instagram</div> </div> <div style="padding: 12.5% 0;"> </div> <div style="display: flex; flex-direction: row; margin-bottom: 14px; align-items: center;"> <div> <div style="background-color: #f4f4f4; border-radius: 50%; height: 12.5px; width: 12.5px; transform: translateX(0px) translateY(7px);"> </div> <div style="background-color: #f4f4f4; height: 12.5px; transform: rotate(-45deg) translateX(3px) translateY(1px); width: 12.5px; flex-grow: 0; margin-right: 14px; margin-left: 2px;"> </div> <div style="background-color: #f4f4f4; border-radius: 50%; height: 12.5px; width: 12.5px; transform: translateX(9px) translateY(-18px);"> </div> </div> <div style="margin-left: 8px;"> <div style="background-color: #f4f4f4; border-radius: 50%; flex-grow: 0; height: 20px; width: 20px;"> </div> <div style="width: 0; height: 0; border-top: 2px solid transparent; border-left: 6px solid #f4f4f4; border-bottom: 2px solid transparent; transform: translateX(16px) translateY(-4px) rotate(30deg);"> </div> </div> <div style="margin-left: auto;"> <div style="width: 0px; border-top: 8px solid #F4F4F4; border-right: 8px solid transparent; transform: translateY(16px);"> </div> <div style="background-color: #f4f4f4; flex-grow: 0; height: 12px; width: 16px; transform: translateY(-4px);"> </div> <div style="width: 0; height: 0; border-top: 8px solid #F4F4F4; border-left: 8px solid transparent; transform: translateY(-4px) translateX(8px);"> </div> </div> </div> <div style="display: flex; flex-direction: column; flex-grow: 1; justify-content: center; margin-bottom: 24px;"> <div style="background-color: #f4f4f4; border-radius: 4px; flex-grow: 0; height: 14px; margin-bottom: 6px; width: 224px;"> </div> <div style="background-color: #f4f4f4; border-radius: 4px; flex-grow: 0; height: 14px; width: 144px;"> </div> </div> <p style="color: #c9c8cd; font-family: Arial,sans-serif; font-size: 14px; line-height: 17px; margin-bottom: 0; margin-top: 8px; overflow: hidden; padding: 8px 0 7px; text-align: center; text-overflow: ellipsis; white-space: nowrap;"><a style="color: #c9c8cd; font-family: Arial,sans-serif; font-size: 14px; font-style: normal; font-weight: normal; line-height: 17px; text-decoration: none;" href="https://www.instagram.com/reel/C7Q68PmJYXV/?utm_source=ig_embed&utm_campaign=loading" target="_blank" rel="noopener">A post shared by 7NEWS Queensland (@7newsqueensland)</a></p> </div> </blockquote> <p>He was then locked in a bitter compensation battle with the airline for several months, which resulted in Lachlan being offered a mere $3,500, which he claims won't "even cover a set of wheels", let alone repair the entire chair. </p> <p>As part of the settlement agreement, which was described by Lachlan as a "signed confidential settlement", he claims he was forced to stay quiet about the amount he was offered by the airline. </p> <p>However, instead of staying quiet, he decided to do the opposite and call out the airline, which has taken a large hit to its reputation in recent years.</p> <p>In a statement provided to <em><a href="https://au.news.yahoo.com/qantas-offers-disabled-aussie-3500-to-stay-quiet-after-damaging-his-wheelchair-225833471.html" target="_blank" rel="noopener">Yahoo News Australia</a></em>, a Qantas spokesperson said they "sincerely apologise to Mr Lachlan for the damage caused to his wheelchair".</p> <p>"We have offered him compensation and are waiting to hear back," a spokesperson said.</p> <p>Lachlan said he would like the incident to serve as a reminder to Qantas, and airlines in general, to be more respectful when it comes to transporting mobility aids.</p> <p>"I am more than happy to meet with them, I invite the CEO of Qantas to jump in this chair and tell me it doesn't need to be replaced," he said.</p> <p><em>Image credits: 7News</em></p>

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After 180 years, new clues are revealing just how general anaesthesia works in the brain

<div class="theconversation-article-body"><em><a href="https://theconversation.com/profiles/adam-d-hines-767066">Adam D Hines</a>, <a href="https://theconversation.com/institutions/queensland-university-of-technology-847">Queensland University of Technology</a></em></p> <p><a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4773932/pdf/BLT.15.159293.pdf/">Over 350 million surgeries</a> are performed globally each year. For most of us, it’s likely at some point in our lives we’ll have to undergo a procedure that needs general anaesthesia.</p> <p>Even though it is one of the safest medical practices, we still don’t have a complete, thorough understanding of precisely how anaesthetic drugs work in the brain.</p> <p>In fact, it has largely remained a mystery since general anaesthesia was introduced into medicine over <a href="https://www.tandfonline.com/doi/full/10.3109/08941939.2015.1061826">180 years ago</a>.</p> <p>Our study published <a href="https://doi.org/10.1523/JNEUROSCI.0588-23.2024">in The Journal of Neuroscience today</a> provides new clues on the intricacies of the process. General anaesthetic drugs seem to only affect specific parts of the brain responsible for keeping us alert and awake.</p> <h2>Brain cells striking a balance</h2> <p>In a study using fruit flies, we found a potential way that allows anaesthetic drugs to interact with specific types of neurons (brain cells), and it’s all to do with proteins. Your brain has around <a href="https://onlinelibrary.wiley.com/doi/10.1002/cne.21974">86 billion neurons</a> and not all of them are the same – it’s these differences that allow general anaesthesia to be effective.</p> <p>To be clear, we’re not completely in the dark on <a href="https://linkinghub.elsevier.com/retrieve/pii/S0165614719300951">how anaesthetic drugs affect us</a>. We know why general anaesthetics are able to make us lose consciousness so quickly, thanks to a <a href="https://www.nature.com/articles/367607a0">landmark discovery made in 1994</a>.</p> <p>But to better understand the fine details, we first have to look to the minute differences between the cells in our brains.</p> <p>Broadly speaking, there are <a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6591655/">two main categories of neurons in the brain</a>.</p> <p>The first are what we call “excitatory” neurons, generally responsible for keeping us alert and awake. The second are “inhibitory” neurons – their job is to regulate and control the excitatory ones.</p> <p>In our day-to-day lives, excitatory and inhibitory neurons are constantly working and balancing one another.</p> <p><a href="https://www.nature.com/articles/npp2017294">When we fall asleep</a>, there are inhibitory neurons in the brain that “silence” the excitatory ones keeping us awake. This happens <a href="https://askdruniverse.wsu.edu/2018/01/07/why-do-we-get-tired/">gradually over time</a>, which is why you may feel progressively more tired through the day.</p> <p>General anaesthetics speed up this process by directly silencing these excitatory neurons without any action from the inhibitory ones. This is why your anaesthetist will tell you that they’ll “put you to sleep” for the procedure: <a href="https://www.nature.com/articles/nrn2372">it’s essentially the same process</a>.</p> <h2>A special kind of sleep</h2> <p>While we know why anaesthetics put us to sleep, the question then becomes: “why do we <em>stay</em> asleep during surgery?”. If you went to bed tonight, fell asleep and somebody tried to do surgery on you, you’d wake up with quite a shock.</p> <p>To date, there is no strong consensus in the field as to why general anaesthesia causes people to remain unconscious during surgery.</p> <p>Over the last couple of decades, researchers have proposed several potential explanations, but they all seem to point to one root cause. <a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7709148/#:%7E:text=At%20presynaptic%20part%2C%20voltage%2Dgated,anesthetics%20to%20inhibiting%20neurotransmitter%20release.">Neurons stop talking to each other</a> when exposed to general anaesthetics.</p> <p>While the idea of “cells talking to each other” may sound a little strange, it’s a <a href="https://qbi.uq.edu.au/brain-basics/brain/brain-physiology/action-potentials-and-synapses">fundamental concept in neuroscience</a>. Without this communication, our brains wouldn’t be able to function at all. And it allows the brain to know what’s happening throughout the body.</p> <figure class="align-center zoomable"><a href="https://images.theconversation.com/files/593888/original/file-20240514-16-5fletd.png?ixlib=rb-4.1.0&amp;q=45&amp;auto=format&amp;w=1000&amp;fit=clip"><img src="https://images.theconversation.com/files/593888/original/file-20240514-16-5fletd.png?ixlib=rb-4.1.0&amp;q=45&amp;auto=format&amp;w=754&amp;fit=clip" sizes="(min-width: 1466px) 754px, (max-width: 599px) 100vw, (min-width: 600px) 600px, 237px" srcset="https://images.theconversation.com/files/593888/original/file-20240514-16-5fletd.png?ixlib=rb-4.1.0&amp;q=45&amp;auto=format&amp;w=600&amp;h=600&amp;fit=crop&amp;dpr=1 600w, https://images.theconversation.com/files/593888/original/file-20240514-16-5fletd.png?ixlib=rb-4.1.0&amp;q=30&amp;auto=format&amp;w=600&amp;h=600&amp;fit=crop&amp;dpr=2 1200w, https://images.theconversation.com/files/593888/original/file-20240514-16-5fletd.png?ixlib=rb-4.1.0&amp;q=15&amp;auto=format&amp;w=600&amp;h=600&amp;fit=crop&amp;dpr=3 1800w, https://images.theconversation.com/files/593888/original/file-20240514-16-5fletd.png?ixlib=rb-4.1.0&amp;q=45&amp;auto=format&amp;w=754&amp;h=754&amp;fit=crop&amp;dpr=1 754w, https://images.theconversation.com/files/593888/original/file-20240514-16-5fletd.png?ixlib=rb-4.1.0&amp;q=30&amp;auto=format&amp;w=754&amp;h=754&amp;fit=crop&amp;dpr=2 1508w, https://images.theconversation.com/files/593888/original/file-20240514-16-5fletd.png?ixlib=rb-4.1.0&amp;q=15&amp;auto=format&amp;w=754&amp;h=754&amp;fit=crop&amp;dpr=3 2262w" alt="Two branching structures in orange, green, blue and yellow colours on a black background." /></a><figcaption><span class="caption">Colourised neurons in the brain of a fly.</span> <span class="attribution"><span class="source">Adam Hines</span></span></figcaption></figure> <h2>What did we discover?</h2> <p>Our new study shows that general anaesthetics appear to stop excitatory neurons from communicating, but not inhibitory ones. <a href="https://www.jneurosci.org/content/40/21/4103">This concept isn’t new</a>, but we found some compelling evidence as to <em>why</em> only excitatory neurons are affected.</p> <p>For neurons to communicate, proteins have to get involved. One of the jobs these proteins have is to get neurons to release molecules called <a href="https://my.clevelandclinic.org/health/articles/22513-neurotransmitters">neurotransmitters</a>. These chemical messengers are what gets signals across from one neuron to another: dopamine, adrenaline and serotonin are all neurotransmitters, for example.</p> <p>We found that general anaesthetics impair the ability of these proteins to release neurotransmitters, but only in excitatory neurons. To test this, we used <a href="https://www.eneuro.org/content/8/3/ENEURO.0057-21.2021"><em>Drosophila melanogaster</em> fruit flies</a> and <a href="https://imb.uq.edu.au/research/facilities/microscopy/training-manuals/microscopy-online-resources/image-capture/super-resolution-microscopy">super resolution microscopy</a> to directly see what effects a general anaesthetic was having on these proteins at a molecular scale.</p> <p>Part of what makes excitatory and inhibitory neurons different from each other is that they <a href="https://journals.physiology.org/doi/full/10.1152/physrev.00007.2012">express different types of the same protein</a>. This is kind of like having two cars of the same make and model, but one is green and has a sports package, while the other is just standard and red. They both do the same thing, but one’s just a little bit different.</p> <p>Neurotransmitter release is a complex process involving lots of different proteins. If one piece of the puzzle isn’t exactly right, then general anaesthetics won’t be able to do their job.</p> <p>As a next research step, we will need to figure out which piece of the puzzle is different, to understand why general anaesthetics only stop excitatory communication.</p> <p>Ultimately, our results hint that the drugs used in general anaesthetics cause massive global inhibition in the brain. By silencing excitability in two ways, these drugs put us to sleep and keep it that way.<!-- Below is The Conversation's page counter tag. Please DO NOT REMOVE. --><img style="border: none !important; box-shadow: none !important; margin: 0 !important; max-height: 1px !important; max-width: 1px !important; min-height: 1px !important; min-width: 1px !important; opacity: 0 !important; outline: none !important; padding: 0 !important;" src="https://counter.theconversation.com/content/229713/count.gif?distributor=republish-lightbox-basic" alt="The Conversation" width="1" height="1" /><!-- End of code. If you don't see any code above, please get new code from the Advanced tab after you click the republish button. The page counter does not collect any personal data. More info: https://theconversation.com/republishing-guidelines --></p> <p><em><a href="https://theconversation.com/profiles/adam-d-hines-767066">Adam D Hines</a>, Research fellow, <a href="https://theconversation.com/institutions/queensland-university-of-technology-847">Queensland University of Technology</a></em></p> <p><em>Image credits: Shutterstock</em></p> <p><em>This article is republished from <a href="https://theconversation.com">The Conversation</a> under a Creative Commons license. Read the <a href="https://theconversation.com/after-180-years-new-clues-are-revealing-just-how-general-anaesthesia-works-in-the-brain-229713">original article</a>.</em></p> </div>

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“My darling wife": Newlywed's tragic death overseas

<p>Madison Noronha (née Chatham) was in Amsterdam with her husband Kyle Noronha after only a few weeks of getting married when she suddenly collapsed on the street. </p> <p>When she was rushed to hospital last week, scans revealed that she had suffered a brain aneurysm and despite getting immediate surgery to relieve the pressure, she unfortunately <span style="font-family: -apple-system, BlinkMacSystemFont, 'Segoe UI', Roboto, Oxygen, Ubuntu, Cantarell, 'Open Sans', 'Helvetica Neue', sans-serif;">could</span><span style="font-family: -apple-system, BlinkMacSystemFont, 'Segoe UI', Roboto, Oxygen, Ubuntu, Cantarell, 'Open Sans', 'Helvetica Neue', sans-serif;"> not be saved. </span></p> <p>“Madi fought like she always does right to the very end,” her heartbroken husband wrote on social media. </p> <p>She passed away in his arms and was surrounded by loved ones. </p> <p>“My darling wife I cannot comprehend what has happened, I’m in a million pieces. Forever and always babe.”</p> <p>Now, her family have set up a <a href="https://www.gofundme.com/f/madison-noronha-chatham" target="_blank" rel="noopener">GoFundMe</a> in attempt to raise funds to “help with flights, funeral costs and to help bring our beloved Madison home to be laid to rest”.</p> <p>Since the launch of the fundraiser, people have come together and raised over $30,000 for the family. </p> <p>Taylah Wicks, the organiser of the fundraiser and a family friend, said that Madison was loved and cherished beyond measure”.</p> <p>“We are all left heart broken, but can’t imagine the pain that Kyle and her immediate family are experiencing,” she wrote on the page.</p> <p><em>Image: GoFundMe</em></p>

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Kick up your heels – ballroom dancing offers benefits to the aging brain and could help stave off dementia

<div class="theconversation-article-body"><em><a href="https://theconversation.com/profiles/helena-blumen-1231899">Helena Blumen</a>, <a href="https://theconversation.com/institutions/albert-einstein-college-of-medicine-3638">Albert Einstein College of Medicine</a></em></p> <h2>The big idea</h2> <p>Social ballroom dancing can improve cognitive functions and reduce brain atrophy in older adults who are at increased risk for Alzheimer’s disease and other forms of dementia. That’s the key finding of my team’s <a href="https://doi.org/10.1123/japa.2022-0176">recently published study</a> in the Journal of Aging and Physical Activity.</p> <p>In our study, we enrolled 25 adults over 65 years of age in either six months of twice-weekly ballroom dancing classes or six months of twice-weekly treadmill walking classes. None of them were engaged in formal dancing or other exercise programs.</p> <p>The overall goal was to see how each experience affected cognitive function and brain health.</p> <p>While none of the study volunteers had a dementia diagnosis, all performed a bit lower than expected on at least one of our dementia screening tests. We found that older adults that completed six months of social dancing and those that completed six months of treadmill walking improved their executive functioning – an umbrella term for planning, reasoning and processing tasks that require attention.</p> <p>Dancing, however, generated significantly greater improvements than treadmill walking on one measure of executive function and on processing speed, which is the time it takes to respond to or process information. Compared with walking, dancing was also associated with reduced brain atrophy in the hippocampus – a brain region that is key to memory functioning and is particularly affected by Alzheimer’s disease. Researchers also know that this part of our brain can undergo neurogenesis – or grow new neurons – <a href="https://doi.org/10.1073/pnas.0611721104">in response to aerobic exercise</a>.</p> <figure><iframe src="https://www.youtube.com/embed/unmbhUvnGow?wmode=transparent&amp;start=0" width="440" height="260" frameborder="0" allowfullscreen="allowfullscreen"></iframe><figcaption><span class="caption">Research shows those who regularly dance with a partner have a more positive outlook on life.</span></figcaption></figure> <p>While several previous studies suggest that dancing has beneficial effects <a href="https://doi.org/10.1093/ageing/afaa270">on cognitive function in older adults</a>, only a few studies have compared it directly with traditional exercises. Our study is the first to observe both better cognitive function and improved brain health following dancing than walking in older adults at risk for dementia. We think that social dancing may be more beneficial than walking because it is physically, socially and cognitively demanding – and therefore strengthens a wide network of brain regions.</p> <p>While dancing, you’re not only using brain regions that are important for physical movement. You’re also relying on brain regions that are important for interacting and adapting to the movements of your dancing partner, as well as those necessary for learning new dance steps or remembering those you’ve learned already.</p> <h2>Why it matters</h2> <p>Nearly 6 million older adults in the U.S. and 55 million worldwide <a href="https://doi.org/10.1016/j.jalz.2019.01.010">have Alzheimer’s disease</a> or a <a href="https://www.who.int/news-room/fact-sheets/detail/dementia">related dementia</a>, yet there is no cure. Sadly, the efficacy and ethics surrounding recently developed drug treatments <a href="https://doi.org/10.1080/21507740.2022.2129858">are still under debate</a>.</p> <p>The good news is that older adults can potentially <a href="https://doi.org/10.1016/S0140-6736(20)30367-6">lower their risk for dementia</a> through lifestyle interventions, even later in life. These include reducing social isolation and physical inactivity.</p> <p>Social ballroom dancing targets both isolation and inactivity. In these later stages of the COVID-19 pandemic, a better understanding of the <a href="https://doi.org/10.1177/23337214211005223">indirect effects of COVID-19</a> – particularly those that increase dementia risk, such as social isolation – is urgently needed. In my view, early intervention is critical to prevent dementia from becoming the next pandemic. Social dancing could be a particularly timely way to overcome the adverse cognitive and brain effects associated with isolation and fewer social interactions during the pandemic.</p> <h2>What still isn’t known</h2> <p>Traditional aerobic exercise interventions such as treadmill-walking or running have been shown to lead to modest but reliable improvements in cognition – <a href="https://doi.org/10.1177/1745691617707316">particularly in executive function</a>.</p> <p>My team’s study builds on that research and provides preliminary evidence that not all exercise is equal when it comes to brain health. Yet our sample size was quite small, and larger studies are needed to confirm these initial findings. Additional studies are also needed to determine the optimal length, frequency and intensity of dancing classes that may result in positive changes.</p> <p>Lifestyle interventions like social ballroom dancing are a promising, noninvasive and cost-effective path toward staving off dementia as we – eventually – leave the COVID-19 pandemic behind.<!-- Below is The Conversation's page counter tag. Please DO NOT REMOVE. --><img style="border: none !important; box-shadow: none !important; margin: 0 !important; max-height: 1px !important; max-width: 1px !important; min-height: 1px !important; min-width: 1px !important; opacity: 0 !important; outline: none !important; padding: 0 !important;" src="https://counter.theconversation.com/content/194969/count.gif?distributor=republish-lightbox-basic" alt="The Conversation" width="1" height="1" /><!-- End of code. If you don't see any code above, please get new code from the Advanced tab after you click the republish button. The page counter does not collect any personal data. More info: https://theconversation.com/republishing-guidelines --></p> <p><em><a href="https://theconversation.com/profiles/helena-blumen-1231899">Helena Blumen</a>, Associate Professor of Medicine and Neurology, <a href="https://theconversation.com/institutions/albert-einstein-college-of-medicine-3638">Albert Einstein College of Medicine</a></em></p> <p><em>Image credits: Shutterstock</em></p> <p><em>This article is republished from <a href="https://theconversation.com">The Conversation</a> under a Creative Commons license. Read the <a href="https://theconversation.com/kick-up-your-heels-ballroom-dancing-offers-benefits-to-the-aging-brain-and-could-help-stave-off-dementia-194969">original article</a>.</em></p> </div>

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Best-selling author diagnosed with "aggressive" brain cancer

<p>Best-selling author Sophie Kinsella has shared that she has been fighting "aggressive" brain cancer since the end of 2022. </p> <p>The British writer took to Instagram to reveal she was diagnosed with glioblastoma 18 months ago, and shared why she chose to keep the devatstsing news out of the spotlight. </p> <p>The 54-year-old said she wanted to "make sure my children were able to hear and process the news in privacy and adapt to our new normal" before going public with her diagnosis. </p> <p>"I have been under the care of the excellent team at University College Hospital in London and have had successful surgery and subsequent radiotherapy and chemotherapy, which is still ongoing," she told her followers on Instagram.</p> <p>"At the moment all is stable and I am feeling generally very well, though I get very tired and my memory is even worse than it was before!"</p> <p>Kinsella said she is "so grateful to my family and close friends who have been an incredible support to me, and to the wonderful doctors and nurses who have treated me."</p> <p>She also thanked her readers for their "constant support", adding how the reception of her latest novel <em>The Burnout</em>, released in October 2023, "really buoyed me up during a difficult time."</p> <p>She ended her statement by saying, "To everyone who is suffering from cancer in any form I send love and best wishes, as well as to those who support them."</p> <p>"It can feel very lonely and scary to have a tough diagnosis, and the support and care of those around you means more than words can say."</p> <p><em>Image credits: Getty Images </em></p>

Caring

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Does intermittent fasting have benefits for our brain?

<p><a href="https://theconversation.com/profiles/hayley-oneill-1458016">Hayley O'Neill</a>, <em><a href="https://theconversation.com/institutions/bond-university-863">Bond University</a></em></p> <p>Intermittent fasting has become a popular dietary approach to help people lose or manage their <a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8683964/">weight</a>. It has also been promoted as a way to reset metabolism, control chronic disease, slow ageing and <a href="https://pubmed.ncbi.nlm.nih.gov/27810402">improve overall health</a>.</p> <p>Meanwhile, some research suggests intermittent fasting may offer a different way for the brain to access energy and provide protection against neurodegenerative diseases like <a href="https://link.springer.com/article/10.1007/s11011-023-01288-2">Alzheimer’s disease</a>.</p> <p>This is not a new idea – the ancient Greeks believed fasting <a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8839325/">enhanced thinking</a>. But what does the modern-day evidence say?</p> <h2>First, what is intermittent fasting?</h2> <p>Our <a href="https://pubmed.ncbi.nlm.nih.gov/35487190/">diets</a> – including calories consumed, macronutrient composition (the ratios of fats, protein and carbohydrates we eat) and when meals are consumed – are factors in our lifestyle we can change. People do this for cultural reasons, desired weight loss or potential health gains.</p> <p>Intermittent fasting consists of short periods of calorie (energy) restriction where food intake is limited for 12 to 48 hours (usually 12 to 16 hours per day), followed by periods of normal food intake. The intermittent component means a re-occurrence of the pattern rather than a “one off” fast.</p> <p>Food deprivation beyond 24 hours typically constitutes starvation. This is distinct from fasting due to its specific and potentially harmful biochemical alterations and nutrient deficiencies if continued for long periods.</p> <h2>4 ways fasting works and how it might affect the brain</h2> <p>The brain accounts for about <a href="https://theconversation.com/how-much-energy-do-we-expend-thinking-and-using-our-brain-197990">20% of the body’s energy consumption</a>.</p> <p>Here are four ways intermittent fasting can act on the body which could help explain its potential effects on the brain.</p> <p><strong>1. Ketosis</strong></p> <p>The goal of many intermittent fasting routines is to flip a “<a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5913738/">metabolic switch</a>” to go from burning predominately carbohydrates to burning fat. This is called ketosis and typically occurs after 12–16 hours of fasting, when liver and glycogen stores are depleted. <a href="https://www.ncbi.nlm.nih.gov/books/NBK493179/">Ketones</a> – chemicals produced by this metabolic process – become the preferred energy source for the brain.</p> <p>Due to this being a slower metabolic process to produce energy and potential for lowering blood sugar levels, ketosis can <a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10844723/">cause symptoms</a> of hunger, fatigue, nausea, <a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8754590/">low mood</a>, irritability, constipation, headaches, and brain “fog”.</p> <p>At the same time, as glucose metabolism in the brain declines with ageing, studies have shown ketones could provide an alternative energy source to <a href="https://www.science.org/doi/10.1126/science.aau2095">preserve brain function</a> and prevent <a href="https://pubmed.ncbi.nlm.nih.gov/32709961/">age-related neurodegeneration disorders and cognitive decline</a>.</p> <p>Consistent with this, increasing ketones through <a href="https://pubmed.ncbi.nlm.nih.gov/31027873/">supplementation</a> or <a href="https://pubmed.ncbi.nlm.nih.gov/31757576/">diet</a> has been shown to improve cognition in adults with mild cognitive decline and those at risk of Alzheimer’s disease respectively.</p> <p><strong>2. Circadian syncing</strong></p> <p>Eating at times that <a href="https://pubmed.ncbi.nlm.nih.gov/32480126/">don’t match our body’s natural daily rhythms</a> can disrupt how our organs work. Studies in shift workers have suggested this might also make us more prone to <a href="https://pubmed.ncbi.nlm.nih.gov/22010477/">chronic disease</a>.</p> <p>Time-restricted eating is when you eat your meals within a six to ten-hour window during the day when you’re most active. Time-restricted eating causes changes in <a href="https://pubmed.ncbi.nlm.nih.gov/36599299/">expression of genes in tissue</a> and helps the body during rest and activity.</p> <p>A 2021 <a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7827225/">study of 883 adults</a> in Italy indicated those who restricted their food intake to ten hours a day were less likely to have cognitive impairment compared to those eating without time restrictions.</p> <p><strong>3. Mitochondria</strong></p> <p>Intermittent fasting may provide <a href="https://pubmed.ncbi.nlm.nih.gov/35218914/">brain protection</a> through improving mitochondrial function, metabolism and reducing oxidants.</p> <p>Mitochondria’s <a href="https://www.genome.gov/genetics-glossary/Mitochondria">main role is to produce energy</a> and they are crucial to brain health. Many age-related diseases are closely related to an energy supply and demand imbalance, likely attributed to <a href="https://www.nature.com/articles/s41574-021-00626-7">mitochondrial dysfunction during ageing</a>.</p> <p>Rodent studies suggest alternate day fasting or reducing calories <a href="https://journals.sagepub.com/doi/10.1038/jcbfm.2014.114">by up to 40%</a> might protect or improve <a href="http://www.ncbi.nlm.nih.gov/pubmed/21861096">brain mitochondrial function</a>. But not all studies support this theory.</p> <p><strong>4. The gut-brain axis</strong></p> <p>The <a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6469458/">gut and the brain communicate with each other</a> via the body’s nervous systems. The brain can influence how the gut feels (think about how you get “butterflies” in your tummy when nervous) and the gut can affect mood, cognition and mental health.</p> <p>In mice, intermittent fasting has shown promise for <a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5913738/">improving brain health</a> by increasing survival and <a href="https://pubmed.ncbi.nlm.nih.gov/12354284/">formation of neurons</a> (nerve cells) in the hippocampus brain region, which is involved in memory, learning and emotion.</p> <p>There’s <a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8470960/">no clear evidence</a> on the effects of intermittent fasting on cognition in healthy adults. However one 2022 study interviewed 411 older adults and found <a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9646955/">lower meal frequency</a> (less than three meals a day) was associated with reduced evidence of Alzheimer’s disease on brain imaging.</p> <p>Some research has suggested calorie restriction may have a protective effect against <a href="https://academic.oup.com/nutritionreviews/article/81/9/1225/7116310">Alzheimer’s disease</a> by reducing oxidative stress and inflammation and promoting vascular health.</p> <p>When we look at the effects of overall energy restriction (rather than intermittent fasting specifically) the evidence is mixed. Among people with mild cognitive impairment, one study showed <a href="https://pubmed.ncbi.nlm.nih.gov/26713821/">cognitive improvement</a> when participants followed a calorie restricted diet for 12 months.</p> <p>Another study found a 25% calorie restriction was associated with <a href="https://pubmed.ncbi.nlm.nih.gov/30968820">slightly improved working memory</a> in healthy adults. But a <a href="https://www.sciencedirect.com/science/article/pii/S0022316623025221?via%3Dihub">recent study</a>, which looked at the impact of calorie restriction on spatial working memory, found no significant effect.</p> <h2>Bottom line</h2> <p>Studies in <a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9740746/">mice</a> support a role for intermittent fasting in improving brain health and ageing, but few studies in humans exist, and the evidence we have is mixed.</p> <p>Rapid weight loss associated with calorie restriction and intermittent fasting can lead to nutrient deficiencies, muscle loss, and decreased immune function, particularly in <a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8749464/">older adults</a> whose nutritional needs may be higher.</p> <p>Further, <a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6314618/">prolonged fasting</a> or <a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9042193/">severe calorie restriction</a> may pose risks such as fatigue, dizziness, and electrolyte imbalances, which could exacerbate existing health conditions.</p> <p>If you’re considering <a href="https://www.nejm.org/doi/10.1056/NEJMra1905136?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub%20%200pubmed">intermittent fasting</a>, it’s best to seek advice from a health professional such as a dietitian who can provide guidance on structuring fasting periods, meal timing, and nutrient intake. This ensures intermittent fasting is approached in a safe, sustainable way, tailored to individual needs and goals.<!-- Below is The Conversation's page counter tag. Please DO NOT REMOVE. --><img style="border: none !important; box-shadow: none !important; margin: 0 !important; max-height: 1px !important; max-width: 1px !important; min-height: 1px !important; min-width: 1px !important; opacity: 0 !important; outline: none !important; padding: 0 !important;" src="https://counter.theconversation.com/content/223181/count.gif?distributor=republish-lightbox-basic" alt="The Conversation" width="1" height="1" /><!-- End of code. If you don't see any code above, please get new code from the Advanced tab after you click the republish button. The page counter does not collect any personal data. More info: https://theconversation.com/republishing-guidelines --></p> <p><a href="https://theconversation.com/profiles/hayley-oneill-1458016">Hayley O'Neill</a>, Assistant Professor, Faculty of Health Sciences and Medicine, <em><a href="https://theconversation.com/institutions/bond-university-863">Bond University</a></em></p> <p><em>This article is republished from <a href="https://theconversation.com">The Conversation</a> under a Creative Commons license. Read the <a href="https://theconversation.com/does-intermittent-fasting-have-benefits-for-our-brain-223181">original article</a>.</em></p> <p><em>Image: Getty </em></p>

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Young boy beats rare brain cancer in world first

<p>A 13-year-old boy from Belgium has become the first person in the world to be cured from a deadly brain cancer. </p> <p>Lucas Jemeljanova was only six-years-old when he was diagnosed with diffuse intrinsic pontine glioma (DIPG), a rare and aggressive brain cancer which kills 98 per cent of sufferers within five years. </p> <p>He was randomly assigned to receive everolimus, a type of chemotherapy drug during a clinical trial. The drug is commonly used to treat kidney, pancreas, breast and brain cancer, but up to this point has not been successfully used to treat DIPG. </p> <p>Seven years later, Lucas has responded well to the treatment and has no trace of cancer, and has officially been in remission for five years.</p> <p>His doctor, Jacques Grill said that Lucas "beat the odds" and his case "offers real hope". </p> <p>Lucas was one of the first few people enrolled in the BIOMEDE trial in France, which was testing potential new drugs for DIPG. </p> <p>The drug works by preventing the cancer cells from reproducing and decreasing blood supply to the cancer cells, and it is an FDA approved prescription drug for cancer.</p> <p>Doctors were initially hesitant to stop the treatment until a year ago and a half ago. </p> <p>"I didn’t know when to stop, or how, because there was no reference in the world," Dr Grill told the <em>AFP</em>. </p> <p>"Over a series of MRI scans, I watched as the tumour completely disappeared," he added. </p> <p>Seven other children who were also in the trial have been considered "long responders", as they haven't had any relapses for three years after their diagnosis, but only Lucas was cured. </p> <p>The reason behind his complete recovery is still unknown, but it could be because of "biological particularities" in his tumour. </p> <p>"Lucas' tumour had an extremely rare mutation which we believe made its cells far more sensitive to the drug," Dr Grill added. </p> <p>DIPG is typically found in children between ages five and nine. </p> <p>The cause of the tumour is unknown but some of the first symptoms include problems with eye movement and balance, facial weakness, difficulty walking and strange limb movements.</p> <p>Researchers are currently trying to reproduce the difference seen in Lucas' cells. </p> <p>"Lucas is believed to have had a particular form of the disease," Dr Grill said. </p> <p>"We must understand what and why to succeed in medically reproducing in other patients what happened naturally with him." </p> <p>However Dr Grill said that this process won't be quick. </p> <p>"On average, it takes 10-15 years from the first lead to become a drug – it's a long and drawn-out process."</p> <p><em>Images: Facebook</em></p> <p> </p>

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Michael Bolton shares shocking health update

<p>Renowned singer Michael Bolton recently shared a shocking revelation with his fans – that he has been diagnosed with brain cancer.</p> <p>The 70-year-old artist famous for his pop-rock ballads underwent immediate surgery just before Christmas, marking the end of 2023 with unexpected challenges. In a heartfelt message on Facebook and Instagram, Bolton expressed gratitude for the success of the surgery and the unwavering support of his medical team, family and fans.</p> <p>In his statement, Bolton disclosed the discovery of a brain tumour just before the holidays, necessitating urgent surgery. Fortunately, the operation was successful, and the singer is currently recuperating at home. Despite the challenging times ahead, Bolton conveyed his determination to focus on recovery and temporarily step back from touring to devote time and energy to the healing process.</p> <p>Acknowledging the difficulty of disappointing fans and postponing shows, Bolton assured his followers that he is working hard to accelerate his recovery and return to the stage as soon as possible. The singer, known for his powerful love songs, expressed gratitude for the positive messages from fans, promising to keep them updated on his progress.</p> <blockquote class="instagram-media" style="background: #FFF; border: 0; border-radius: 3px; box-shadow: 0 0 1px 0 rgba(0,0,0,0.5),0 1px 10px 0 rgba(0,0,0,0.15); margin: 1px; max-width: 540px; min-width: 326px; padding: 0; width: calc(100% - 2px);" data-instgrm-captioned="" data-instgrm-permalink="https://www.instagram.com/p/C1vGsEdv07S/?utm_source=ig_embed&utm_campaign=loading" data-instgrm-version="14"> <div style="padding: 16px;"> <div style="display: flex; flex-direction: row; align-items: center;"> <div style="background-color: #f4f4f4; border-radius: 50%; flex-grow: 0; height: 40px; margin-right: 14px; width: 40px;"> </div> <div style="display: flex; flex-direction: column; flex-grow: 1; justify-content: center;"> <div style="background-color: #f4f4f4; border-radius: 4px; flex-grow: 0; height: 14px; margin-bottom: 6px; width: 100px;"> </div> <div style="background-color: #f4f4f4; border-radius: 4px; flex-grow: 0; height: 14px; width: 60px;"> </div> </div> </div> <div style="padding: 19% 0;"> </div> <div style="display: block; height: 50px; margin: 0 auto 12px; width: 50px;"> </div> <div style="padding-top: 8px;"> <div style="color: #3897f0; font-family: Arial,sans-serif; font-size: 14px; font-style: normal; font-weight: 550; line-height: 18px;">View this post on Instagram</div> </div> <div style="padding: 12.5% 0;"> </div> <div style="display: flex; flex-direction: row; margin-bottom: 14px; align-items: center;"> <div> <div style="background-color: #f4f4f4; border-radius: 50%; height: 12.5px; width: 12.5px; transform: translateX(0px) translateY(7px);"> </div> <div style="background-color: #f4f4f4; height: 12.5px; transform: rotate(-45deg) translateX(3px) translateY(1px); width: 12.5px; flex-grow: 0; margin-right: 14px; margin-left: 2px;"> </div> <div style="background-color: #f4f4f4; border-radius: 50%; height: 12.5px; width: 12.5px; transform: translateX(9px) translateY(-18px);"> </div> </div> <div style="margin-left: 8px;"> <div style="background-color: #f4f4f4; border-radius: 50%; flex-grow: 0; height: 20px; width: 20px;"> </div> <div style="width: 0; height: 0; border-top: 2px solid transparent; border-left: 6px solid #f4f4f4; border-bottom: 2px solid transparent; transform: translateX(16px) translateY(-4px) rotate(30deg);"> </div> </div> <div style="margin-left: auto;"> <div style="width: 0px; border-top: 8px solid #F4F4F4; border-right: 8px solid transparent; transform: translateY(16px);"> </div> <div style="background-color: #f4f4f4; flex-grow: 0; height: 12px; width: 16px; transform: translateY(-4px);"> </div> <div style="width: 0; height: 0; border-top: 8px solid #F4F4F4; border-left: 8px solid transparent; transform: translateY(-4px) translateX(8px);"> </div> </div> </div> <div style="display: flex; flex-direction: column; flex-grow: 1; justify-content: center; margin-bottom: 24px;"> <div style="background-color: #f4f4f4; border-radius: 4px; flex-grow: 0; height: 14px; margin-bottom: 6px; width: 224px;"> </div> <div style="background-color: #f4f4f4; border-radius: 4px; flex-grow: 0; height: 14px; width: 144px;"> </div> </div> <p style="color: #c9c8cd; font-family: Arial,sans-serif; font-size: 14px; line-height: 17px; margin-bottom: 0; margin-top: 8px; overflow: hidden; padding: 8px 0 7px; text-align: center; text-overflow: ellipsis; white-space: nowrap;"><a style="color: #c9c8cd; font-family: Arial,sans-serif; font-size: 14px; font-style: normal; font-weight: normal; line-height: 17px; text-decoration: none;" href="https://www.instagram.com/p/C1vGsEdv07S/?utm_source=ig_embed&utm_campaign=loading" target="_blank" rel="noopener">A post shared by Michael Bolton (@michaelbolton)</a></p> </div> </blockquote> <p>Prior to his revelation, fans had expressed concerns about Bolton's health following his performance during the Disney Parks Christmas Day Parade. Some viewers noted that he appeared to be in pain, sparking speculation about his well-being.</p> <p>Bolton gained fame in the late 1980s for his transition from heavy metal to power ballads, earning recognition for his emotive love songs. Throughout his illustrious career, he amassed six American Music Awards, two Grammy Awards, and achieved chart-topping success with two number-one singles on the Billboard charts.</p> <p>Beyond his musical achievements, Bolton showcased his versatility by participating in various entertainment ventures. Notably, his appearance in The Lonely Island's viral video "Jack Sparrow" garnered widespread attention, accumulating over 200 million views. He also co-hosted ABC's <em>Celebrity Dating Game</em> and delved into acting with roles in shows like <em>Meet Wally Sparks</em>, <em>Two and a Half Men</em>, and a stint on <em>Dancing with the Stars US</em>.</p> <p>Despite his success, Bolton faced financial setbacks in 1992 when he was sued by the Isley Brothers for alleged song theft. The legal battle concluded in 2001, with substantial payments made to the Isley Brothers. Bolton's personal life has seen its share of ups and downs, including a marriage to Maureen McGuire that ended in 1990, and a subsequent relationship with Nicollette Sheridan.</p> <p>Bolton's announcement of his battle with brain cancer has left fans shocked and concerned for the beloved singer. As he embarks on the path to recovery, the outpouring of support from fans and well-wishers reflects the impact he has had on the music industry and in the hearts of those who have followed his journey.</p> <p><em>Images: Instagram</em></p>

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"Betrayed": Shannen Doherty opens up on tough divorce amid cancer battle

<p>Shannen Doherty revealed it all on the debut episode of her new podcast <em>Let’s Be Clear with Shannen Doherty</em>. </p> <p>The actress opened up on her tough split from her husband of 14 years, Kurt Iswarienko, after she found out he had been having an affair for two years, while she was battling brain cancer.</p> <p>She recalled the moment she found out, right before her surgery to remove the tumour in January. </p> <p>“I went into that surgery early in the morning and I went in after I found out that my marriage was essentially over, that my husband had been carrying on an affair for two years,” she said. </p> <p>“To not go in that surgery, even though, being very clear, he wanted to go, I couldn’t go into that surgery with him there. I felt so betrayed.”</p> <p>“At the end of the day, I just felt so incredibly unloved by someone I was with for 14 years, by someone I loved with all my heart,” Doherty continued, adding that she had her family and friends by her side. </p> <p>Though the<em> Charmed </em>actress is currently focusing on her health and the future, she did admit that the entire experience has been overwhelming. </p> <p>“Just to have to go through all of that while trying to figure out if you’re going to get a frickin’ divorce and trying to get to the truth of that,” she said. </p> <p>She added that she was "obsessed" with finding out the truth of the affair, “through conversations, expecting someone to be honest with me.”</p> <p>“If you share 14 years together and you cheated, doesn’t that person deserve the absolute truth regardless of how much that hurts them? If they’re the ones asking for it, if they’re the ones saying, ‘Listen, I get it, I may cry, I may get angry, and this may really suck to hear, but I need to hear it because I need closure and this is how I get my closure.’ So I had a lot of months of trying to figure out what I was going to do,” she explained.</p> <p>She added that the reason why she was trying so hard to make sense of the situation was because she herself does not condone cheating, “If you cheat on me, you’re out," she said. </p> <p>“Then when someone you really, really love, someone that you regard as your absolute best friend in the world, when you’re lied to and you discover they cheated on you, or they finally tell you they’re cheating on you because they’re riddled by guilt or whatever, I didn’t walk away. I couldn’t. I was so confused.”</p> <p>She added that the confusion was also a side effect from her surgery as she was undertaking a bunch of medication and steroids to prevent her brain from swelling. </p> <p>Doherty and Iswarienko tied the knot in 2011 and filed for divorce earlier this year in April. </p> <p>The actress revealed that she struggled with her decision to file for divorce, and did talk to “girlfriend of two years that he cheated on me with.” </p> <p>“And honestly, it’s still really hard. Yes, I made the decision to file for divorce, but I have a lot of memories with this person,” she said. </p> <p>She added that although she takes responsibility for some of the issues in their marriage, she does not take responsibility for the "demise" of it. </p> <p>“I take responsibility not only because of how I was but because of how cancer impacted my marriage and how it impacted him the second time around," she said. </p> <p>"I do not take responsibility for the demise of our marriage because I am not a quitter. If somebody is still showing me loyalty and respect and love, I’m going to hang in there. I’m going to try my hardest," she added. </p> <p>Despite three failed marriages, the actress said that she still believes in love. </p> <p><em>Images: Getty</em></p>

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Little girl's Anzac artwork sells at auction for $100,000

<p>A moving artwork created by nine-year-old Evie Poolman has sold for a staggering six-figure sum at auction. </p> <p>Young Evie created the artwork of the 'Lone Soldier' just six months after receiving a devastating diagnosis of diffuse intrinsic pontine glioma (DIPG), a deadly type of brain tumour.</p> <p>Evie underwent four brain surgeries and 30 rounds of radiation for her condition but tragically died at the age of nine in June 2021.</p> <p>Now, the artwork - a striking red and orange piece depicting an Anzac standing before a grave at sunset - has been auctioned off by Evie's parents in an attempt to raise money for a cure for the horrible disease. </p> <p>Currently, DIPG has a zero per cent survival rate but despite this, since 2015, less than a million dollars has been dedicated to research in Australia.</p> <p>Evie's parents Chuck and Bridget chose to auction off their late daughter's artwork at the Heels 2 Heal charity lunch in Sydney on Friday, to increase the funding of research into DIPG. </p> <p>The lucky winner, Jo Kinghorn, forked out a staggering $100,000 for the artwork, as she handed over the money "with absolute joy and pleasure".</p> <p>"It was so exciting for me, I've never really experienced anything like that before," Kinghorn, a friend of the Poolman family, told 2GB's Ben Fordham, adding that she hadn't woken up that day expecting to part with so much money.</p> <p>"I'm just so grateful that the painting ended up in my hands."</p> <p>Kinghorn was more than happy to contribute so much money, knowing the funds were going to a good cause. </p> <p>"It's a drop in the ocean as to what is needed, and the government has the ability to properly fund these trials," Kinghorn said of the money spent.</p> <p>"I saw first-hand what this did to a family, and the strength of this family is beyond words. I cannot be more proud. It's just devastating."</p> <p><em>Image credits: 2GB</em></p>

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Britney Spears’ memoir is a reminder of the stigma and potential damage of child stardom

<p><em><a href="https://theconversation.com/profiles/jane-oconnor-1483447">Jane O’Connor</a>, <a href="https://theconversation.com/institutions/birmingham-city-university-920">Birmingham City University</a></em></p> <p>Britney Spears’ new memoir, The Woman in Me, illustrates once again the potential lifelong damage that can be caused by being a child star. Like many before her, including <a href="https://www.britannica.com/biography/Judy-Garland">Judy Garland</a> and <a href="https://www.britannica.com/biography/Michael-Jackson">Michael Jackson</a>, Spears was ushered into the dangerous terrain of childhood fame by the adults who were supposed to be protecting her, and was utterly unprepared to deal with the fallout.</p> <p>Spears’ <a href="https://www.bbc.co.uk/news/world-us-canada-53494405">father’s conservatorship</a>, controlling every aspect of her personal and professional life, was finally rescinded in 2021. She is now able to share the details of her extraordinary years in the limelight and beyond.</p> <p>From a sociological perspective, childhood is considered socially constructed. This means that there are specific ways of raising children which are socially and culturally defined. We discard these conventions surrounding the early years of life at our peril.</p> <p>The boundaries and rules around what is and is not acceptable during childhood, and the normal activities and institutions that shape the experience of being a child have developed over the centuries for a reason – to try and keep children safe from the harsh realities of the adult world.</p> <p>Being sexualised and valued for your appearance, being paid to work, having to deal with criticism and unwanted attention from strangers – these are all difficult aspects of growing up. Children and teens need careful support and guidance if they are to navigate safely into their adult lives and identities.</p> <p>The experience of childhood fame throws aside this social safety net for children in every possible way, and the consequences can be disastrous.</p> <h2>The price of child fame</h2> <p>From the earliest child stars of Hollywood’s golden age, through the television sitcoms and shows of the mid-20th century, the rise of the pop and film industries in the following decades and the burst in popularity of reality TV and talent shows of the early 21st century, <a href="https://www.tandfonline.com/doi/abs/10.1080/17482798.2011.584378">children have always featured</a>. Many have paid a heavy price for their often short period of fame.</p> <p>Sad stories of <a href="https://www.or-nc.com/why-do-child-stars-become-addicted-to-drugs/">drug and alcohol addiction</a>, <a href="https://www.hitc.com/en-gb/2022/11/02/uncle-fester-star-jackie-coogans-tragic-life-child-fortune-to-horror-crash">family disputes</a>, <a href="https://www.ranker.com/list/child-actors-who-became-criminals/nathan-gibso">criminal activity</a> and <a href="https://www.dailystar.co.uk/showbiz/us-showbiz/former-nickelodeon-star-drake-bells-29769568">toxic relationships</a> are frequently reported by the media. These reinforce the stereotypical “child star gone bad” and “too much too young” narratives that the wider public has come to expect.</p> <p>For example, stories abound of <a href="https://metro.co.uk/2020/02/11/macaulay-culkin-reveals-never-divorced-parents-emancipated-12222457/">Macaulay Culkin “divorcing” his controlling parents</a> and his difficulties transitioning into adult life, <a href="https://www.belfasttelegraph.co.uk/entertainment/film-tv/why-it-was-not-a-wonderful-life-for-macaulay-culkin-after-he-found-fame-in-the-hit-christmas-film-home-alone/37620091.html">feeling trapped</a> in the image of boyhood innocence of his most famous character, Kevin in the Home Alone movies.</p> <p><a href="https://books.google.co.uk/books?id=kSJ8XjTw10kC&amp;printsec=frontcover&amp;redir_esc=y#v=onepage&amp;q&amp;f=false">In her autobiography</a> actor Drew Barrymore has written about her casual acceptance at Hollywood parties and consumption of alcohol at a very young age, following her role in <a href="https://www.imdb.com/title/tt0083866/">E.T.</a> (1982) aged five.</p> <p>There is also the tragic life and death of <a href="https://www.theguardian.com/tv-and-radio/2010/may/29/gary-coleman-obituary">Gary Coleman</a>, cute kid star of the American sitcom <a href="https://www.imdb.com/title/tt0077003/">Diff'rent Strokes</a> (1978-1986).</p> <p>Coleman, who died at 42 following a history of <a href="https://nypost.com/2010/05/29/troubled-80s-child-star-gary-colemans-life-is-cut-short-at-42/#:%7E:text=In%202005%2C%20Coleman%20moved%20to,and%20%22wanted%20to%20die.%22">substance abuse</a> and <a href="https://www.salon.com/2010/05/28/gary_coleman_dies/">depression</a>, reported being <a href="https://www.theguardian.com/tv-and-radio/2010/may/29/gary-coleman-obituary">deeply humiliated</a> by people asking: “Didn’t you used to be …?” when he was working as a security guard at a supermarket as an adult.</p> <h2>Other possibilities</h2> <p>It’s important to note, however, that a difficult trajectory is not the experience of all child stars and former child stars. The actors from the Harry Potter films, for example, seem <a href="https://www.theguardian.com/film/2021/oct/22/the-not-so-cursed-child-did-harry-potter-mark-the-end-of-troubled-young-actors">largely to have transitioned well</a> into adult lives and careers – some in the spotlight, others not.</p> <p>And the new generation of famous children and teens such as <a href="https://www.gq.com/story/stranger-things-millie-bobby-brown">Millie Bobby Brown</a>, star of the Netflix show <a href="https://theconversation.com/stranger-things-is-the-upside-down-to-disneys-cute-and-cuddly-universe-83417">Stranger Things</a> (2016-present), seem more prepared for fame than their predecessors, in control of their images and identities via their own social media platforms and <a href="https://www.bbc.co.uk/news/world-44045291">potentially protected to some extent</a> from extreme sexualisation by the MeToo movement.</p> <p>Even so, Brown <a href="https://www.popbuzz.com/tv-film/news/millie-bobby-brown-birthday-instagram-post/">commented on her 16th birthday</a> that: “There are moments I get frustrated from the inaccuracy, inappropriate comments, sexualization, and unnecessary insults.”</p> <p>For Spears though, these were more than moments. She details in her memoir how the constant public scrutiny of her body and physical appearance, being valued for her sexuality and treated as a commodity have characterised her entire life.</p> <p>It is no wonder <a href="https://people.com/britney-spears-reveals-why-shaved-off-hair-in-2007-exclusive-8362494">she shaved her head</a> in 2007, a move interpreted by the media as her having “gone mad”, but in fact a powerful indication of her anger at being perceived as nothing more than a dancing sex-doll. As she writes in her memoir: "I knew a lot of guys thought long hair was hot. Shaving my head was a way of saying to the world: fuck you. You want me to be pretty for you? Fuck you. You want me to be good for you? Fuck you. You want me to be your dream girl? Fuck you."</p> <p>The sociologist Erving Goffman wrote about the stigma of having a “<a href="https://www.howcommunicationworks.com/blog/2020/12/16/what-is-stigma-explaining-goffmans-idea-of-spoiled-identity">spoiled identity</a>” whereby people carry with them the public shame of transgression or physical difference.</p> <p>Being a former child star can be stigmatising for many reasons, including being constantly compared to an ideal younger version of yourself and not having had a “normal” childhood or conventional family relationships.</p> <p>In this memoir, Britney attempts to face down that stigma and reclaim her identity and person-hood as an adult. In doing so, she demonstrates that it can be possible to leave the dangerous terrain of early fame behind – but the journey is a tough one.<!-- End of code. If you don't see any code above, please get new code from the Advanced tab after you click the republish button. The page counter does not collect any personal data. More info: https://theconversation.com/republishing-guidelines --></p> <p><em><a href="https://theconversation.com/profiles/jane-oconnor-1483447">Jane O’Connor</a>, Reader in Childhood Studies, <a href="https://theconversation.com/institutions/birmingham-city-university-920">Birmingham City University</a></em></p> <p><em>Image credits: Getty Images / Instagram, </em></p> <p><em>This article is republished from <a href="https://theconversation.com">The Conversation</a> under a Creative Commons license. Read the <a href="https://theconversation.com/britney-spears-memoir-is-a-reminder-of-the-stigma-and-potential-damage-of-child-stardom-216545">original article</a>.</em></p>

Music

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Does running water really trigger the urge to pee? Experts explain the brain-bladder connection

<p><em><a href="https://theconversation.com/profiles/james-overs-1458017">James Overs</a>, <a href="https://theconversation.com/institutions/swinburne-university-of-technology-767">Swinburne University of Technology</a>; <a href="https://theconversation.com/profiles/david-homewood-1458022">David Homewood</a>, <a href="https://theconversation.com/institutions/melbourne-health-950">Melbourne Health</a>; <a href="https://theconversation.com/profiles/helen-elizabeth-oconnell-ao-1458226">Helen Elizabeth O'Connell AO</a>, <a href="https://theconversation.com/institutions/the-university-of-melbourne-722">The University of Melbourne</a>, and <a href="https://theconversation.com/profiles/simon-robert-knowles-706104">Simon Robert Knowles</a>, <a href="https://theconversation.com/institutions/swinburne-university-of-technology-767">Swinburne University of Technology</a></em></p> <p>We all know that feeling when nature calls – but what’s far less understood is the psychology behind it. Why, for example, do we get the urge to pee just before getting into the shower, or when we’re swimming? What brings on those “nervous wees” right before a date?</p> <p>Research suggests our brain and bladder are in constant communication with each other via a neural network called the <a href="https://www.einj.org/journal/view.php?doi=10.5213/inj.2346036.018">brain-bladder axis</a>.</p> <p>This complex web of circuitry is comprised of sensory neural activity, including the sympathetic and parasympathetic nervous systems. These neural connections allow information to be sent <a href="https://doi.org/10.3390/diagnostics12123119">back and forth</a> between the brain and bladder.</p> <p>The brain-bladder axis not only facilitates the act of peeing, but is also responsible for telling us we need to go in the first place.</p> <h2>How do we know when we need to go?</h2> <p>As the bladder fills with urine and expands, this activates special receptors detecting stretch in the nerve-rich lining of the bladder wall. This information is then relayed to the “periaqueductal gray” – a part of the brain in the brainstem which <a href="https://www.nature.com/articles/nrn2401">constantly monitors</a> the bladder’s filling status.</p> <figure class="align-center zoomable"><a href="https://images.theconversation.com/files/547931/original/file-20230913-19-2kgkhk.jpg?ixlib=rb-1.1.0&amp;q=45&amp;auto=format&amp;w=1000&amp;fit=clip"><img src="https://images.theconversation.com/files/547931/original/file-20230913-19-2kgkhk.jpg?ixlib=rb-1.1.0&amp;q=45&amp;auto=format&amp;w=754&amp;fit=clip" sizes="(min-width: 1466px) 754px, (max-width: 599px) 100vw, (min-width: 600px) 600px, 237px" srcset="https://images.theconversation.com/files/547931/original/file-20230913-19-2kgkhk.jpg?ixlib=rb-1.1.0&amp;q=45&amp;auto=format&amp;w=600&amp;h=454&amp;fit=crop&amp;dpr=1 600w, https://images.theconversation.com/files/547931/original/file-20230913-19-2kgkhk.jpg?ixlib=rb-1.1.0&amp;q=30&amp;auto=format&amp;w=600&amp;h=454&amp;fit=crop&amp;dpr=2 1200w, https://images.theconversation.com/files/547931/original/file-20230913-19-2kgkhk.jpg?ixlib=rb-1.1.0&amp;q=15&amp;auto=format&amp;w=600&amp;h=454&amp;fit=crop&amp;dpr=3 1800w, https://images.theconversation.com/files/547931/original/file-20230913-19-2kgkhk.jpg?ixlib=rb-1.1.0&amp;q=45&amp;auto=format&amp;w=754&amp;h=570&amp;fit=crop&amp;dpr=1 754w, https://images.theconversation.com/files/547931/original/file-20230913-19-2kgkhk.jpg?ixlib=rb-1.1.0&amp;q=30&amp;auto=format&amp;w=754&amp;h=570&amp;fit=crop&amp;dpr=2 1508w, https://images.theconversation.com/files/547931/original/file-20230913-19-2kgkhk.jpg?ixlib=rb-1.1.0&amp;q=15&amp;auto=format&amp;w=754&amp;h=570&amp;fit=crop&amp;dpr=3 2262w" alt="" /></a><figcaption><span class="caption">The periaqueductal gray is a section of gray matter located in the midbrain section of the brainstem.</span> <span class="attribution"><a class="source" href="https://en.wikipedia.org/wiki/Brainstem#/media/File:1311_Brain_Stem.jpg">Wikimedia/OpenStax</a>, <a class="license" href="http://creativecommons.org/licenses/by-sa/4.0/">CC BY-SA</a></span></figcaption></figure> <p>Once the bladder reaches a certain threshold (roughly 250-300ml of urine), another part of the brain called the “pontine micturition centre” is activated and signals that the bladder needs to be emptied. We, in turn, <a href="https://pubmed.ncbi.nlm.nih.gov/16254993/">register this</a> as that all-too-familiar feeling of fullness and pressure down below.</p> <p>Beyond this, however, a range of situations can trigger or exacerbate our need to pee, by increasing the production of urine and/or stimulating reflexes in the bladder.</p> <h2>Peeing in the shower</h2> <p>If you’ve ever felt the need to pee while in the shower (no judgement here) it may be due to the sight and sound of running water.</p> <p>In a 2015 study, <a href="https://doi.org/10.1371/journal.pone.0126798">researchers demonstrated</a> that males with urinary difficulties found it easier to initiate peeing when listening to the sound of running water being played on a smartphone.</p> <p>Symptoms of overactive bladder, including urgency (a sudden need to pee), have also been <a href="https://www.alliedacademies.org/articles/environmental-cues-to-urgency-and-incontinence-episodes-in-chinesepatients-with-overactive-urinary-bladder-syndrome.html">linked to</a> a range of environmental cues involving running water, including washing your hands and taking a shower.</p> <p>This is likely due to both physiology and psychology. Firstly, the sound of running water may have a relaxing <em>physiological</em> effect, increasing activity of the parasympathetic nervous system. This would relax the bladder muscles and prepare the bladder for emptying.</p> <p>At the same time, the sound of running water may also have a conditioned <em>psychological</em> effect. Due to the countless times in our lives where this sound has coincided with the actual act of peeing, it may trigger an instinctive reaction in us to urinate.</p> <p>This would happen in the same way <a href="https://www.simplypsychology.org/pavlov.html">Pavlov’s dog learnt</a>, through repeated pairing, to salivate when a bell was rung.</p> <h2>Cheeky wee in the sea</h2> <p>But it’s not just the sight or sound of running water that makes us want to pee. Immersion in cold water has been shown to cause a “cold shock response”, <a href="https://pubmed.ncbi.nlm.nih.gov/19945970">which activates</a> the sympathetic nervous system.</p> <p>This so-called “fight or flight” response drives up our blood pressure which, in turn, causes our kidneys to filter out more fluid from the bloodstream to stabilise our blood pressure, in a process called “<a href="https://link.springer.com/article/10.1007/BF00864230">immersion diuresis</a>”. When this happens, our bladder fills up faster than normal, triggering the urge to pee.</p> <p>Interestingly, immersion in very warm water (such as a relaxing bath) may also increase urine production. In this case, however, it’s due to activation of the parasympathetic nervous system. <a href="https://doi.org/10.1007/s004210050065">One study</a> demonstrated an increase in water temperature from 40℃ to 50℃ reduced the time it took for participants to start urinating.</p> <p>Similar to the effect of hearing running water, the authors of the study suggest being in warm water is calming for the body and activates the parasympathetic nervous system. This activation can result in the relaxation of the bladder and possibly the pelvic floor muscles, bringing on the urge to pee.</p> <h2>The nervous wee</h2> <p>We know stress and anxiety can cause bouts of nausea and butterflies in the tummy, but what about the bladder? Why do we feel a sudden and frequent urge to urinate at times of heightened stress, such as before a date or job interview?</p> <p>When a person becomes stressed or anxious, the body goes into fight-or-flight mode through the activation of the sympathetic nervous system. This triggers a cascade of physiological changes designed to prepare the body to face a perceived threat.</p> <p>As part of this response, the muscles surrounding the bladder may contract, leading to a more urgent and frequent need to pee. Also, as is the case during immersion diuresis, the increase in blood pressure associated with the stress response may <a href="https://doi.org/10.1172/JCI102496">stimulate</a> the kidneys to produce more urine.</p> <h2>Some final thoughts</h2> <p>We all pee (most of us several times a day). Yet <a href="https://doi.org/10.5489/cuaj.1150">research has shown</a> about 75% of adults know little about how this process actually works – and even less about the brain-bladdder axis and its role in urination.</p> <p><a href="https://www.continence.org.au/about-us/our-work/key-statistics-incontinence#:%7E:text=Urinary%20incontinence%20affects%20up%20to,38%25%20of%20Australian%20women1.">Most Australians</a> will experience urinary difficulties at some point in their lives, so if you ever have concerns about your urinary health, it’s extremely important to consult a healthcare professional.</p> <p>And should you ever find yourself unable to pee, perhaps the sight or sound of running water, a relaxing bath or a nice swim will help with getting that stream to flow.<!-- Below is The Conversation's page counter tag. Please DO NOT REMOVE. --><img style="border: none !important; box-shadow: none !important; margin: 0 !important; max-height: 1px !important; max-width: 1px !important; min-height: 1px !important; min-width: 1px !important; opacity: 0 !important; outline: none !important; padding: 0 !important;" src="https://counter.theconversation.com/content/210808/count.gif?distributor=republish-lightbox-basic" alt="The Conversation" width="1" height="1" /><!-- End of code. If you don't see any code above, please get new code from the Advanced tab after you click the republish button. The page counter does not collect any personal data. More info: https://theconversation.com/republishing-guidelines --></p> <p><a href="https://theconversation.com/profiles/james-overs-1458017"><em>James Overs</em></a><em>, Research Assistant, <a href="https://theconversation.com/institutions/swinburne-university-of-technology-767">Swinburne University of Technology</a>; <a href="https://theconversation.com/profiles/david-homewood-1458022">David Homewood</a>, Urology Research Registrar, Western Health, <a href="https://theconversation.com/institutions/melbourne-health-950">Melbourne Health</a>; <a href="https://theconversation.com/profiles/helen-elizabeth-oconnell-ao-1458226">Helen Elizabeth O'Connell AO</a>, Professor, University of Melbourne, Department of Surgery. President Urological Society Australia and New Zealand, <a href="https://theconversation.com/institutions/the-university-of-melbourne-722">The University of Melbourne</a>, and <a href="https://theconversation.com/profiles/simon-robert-knowles-706104">Simon Robert Knowles</a>, Associate Professor and Clinical Psychologist, <a href="https://theconversation.com/institutions/swinburne-university-of-technology-767">Swinburne University of Technology</a></em></p> <p><em>Image credits: Getty Images</em></p> <p><em>This article is republished from <a href="https://theconversation.com">The Conversation</a> under a Creative Commons license. Read the <a href="https://theconversation.com/does-running-water-really-trigger-the-urge-to-pee-experts-explain-the-brain-bladder-connection-210808">original article</a>.</em></p>

Mind

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The science of dreams and nightmares – what is going on in our brains while we’re sleeping?

<p><em><a href="https://theconversation.com/profiles/drew-dawson-13517">Drew Dawson</a>, <a href="https://theconversation.com/institutions/cquniversity-australia-2140">CQUniversity Australia</a> and <a href="https://theconversation.com/profiles/madeline-sprajcer-1315489">Madeline Sprajcer</a>, <a href="https://theconversation.com/institutions/cquniversity-australia-2140">CQUniversity Australia</a></em></p> <p>Last night you probably slept for <a href="https://www.sciencedirect.com/science/article/pii/S2352721816301292">seven to eight hours</a>. About one or two of these was likely in deep sleep, especially if you’re young or physically active. That’s because <a href="http://apsychoserver.psych.arizona.edu/jjbareprints/psyc501a/readings/Carskadon%20Dement%202011.pdf">sleep changes with age</a> and <a href="https://www.hindawi.com/journals/apm/2017/1364387/">exercise</a> affects brain activity. About three or four hours will have been spent in light sleep.</p> <p>For the remaining time, you were likely in rapid eye movement (REM) sleep. While this is not the only time your brain is potentially dreaming – we also dream during other sleep stages – it is the time your brain activity is most likely to be recalled and reported when you’re awake.</p> <p>That’s usually because either really weird thoughts or feelings wake you up or because the last hour of sleep is nearly all <a href="https://www.researchgate.net/profile/Elizaveta-Solomonova/publication/320356182_Dream_Recall_and_Content_in_Different_Stages_of_Sleep_and_Time-of-Night_Effect/links/5a707bdb0f7e9ba2e1cade56/Dream-Recall-and-Content-in-Different-Stages-of-Sleep-and-Time-of-Night-Effect.pdf">REM sleep</a>. When dreams or your alarm wake you, you’re likely coming out of dream sleep and your dream often lingers into the first few minutes of being awake. In this case you remember it.</p> <p>If they’re strange or interesting dreams, you might tell someone else about them, which may further <a href="https://link.springer.com/article/10.1007/s00426-022-01722-7">encode</a> the dream memory.</p> <p>Dreams and nightmares are mysterious and we’re still learning about them. They keep our brains ticking over. They wash the thoughts from the day’s events at a molecular level. They might even help us imagine what’s possible during our waking hours.</p> <h2>What do scientists know about REM sleep and dreaming?</h2> <p>It’s really hard to study dreaming because people are asleep and we can’t observe what’s going on. Brain imaging has indicated certain <a href="https://www.sciencedirect.com/science/article/pii/S1087079216300673#sec3">patterns of brain activity</a> are associated with dreaming (and with certain sleep stages where dreams are more likely to occur). But such studies ultimately rely on self-reports of the dream experience.</p> <p>Anything we spend so much time doing probably serves multiple ends.</p> <p>At the basic physiological level (indicated by <a href="https://www.sciencedirect.com/science/article/pii/S1053810021001409">brain activity, sleep behaviour and studies of conciousness</a>), all mammals dream – even the platypus and echidna probably experience something similar to dreaming (provided they are at the <a href="https://www.wired.com/2014/07/the-creature-feature-10-fun-facts-about-the-echidna/#:%7E:text=It%20was%20long%20thought%20that,re%20at%20the%20right%20temperature.">right temperature</a>). Their brain activity and sleep stages align to some degree with human <a href="https://www.sciencedirect.com/science/article/pii/S1053810021001409#b0630">REM sleep</a>.</p> <p>Less evolved species do not. Some <a href="https://www.sciencedirect.com/science/article/pii/S2468867319301993#sec0030">jellyfish</a> – who do not have a brain – do experience what could physiologically be characterised as sleep (shown by their posture, quietness, lack of responsiveness and rapid “waking” when prompted). But they do not experience the same physiological and behavioural elements that resemble REM dream sleep.</p> <p>In humans, REM sleep is thought to occur cyclically every 90 to 120 minutes across the night. It prevents us from sleeping too deeply and being <a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4972941/">vulnerable to attack</a>. Some scientists think we dream in order to stop our brains and bodies from getting too cold. Our core body temperature is typically <a href="https://www.thelancet.com/journals/laneur/article/PIIS1474-4422(22)00210-1/fulltext">higher while dreaming</a>. It is typically easier to <a href="https://www.tandfonline.com/doi/pdf/10.2147/NSS.S188911">wake from dreaming</a> if we need to respond to external cues or dangers.</p> <p>The brain activity in REM sleep kicks our brain into gear for a bit. It’s like a periscope into a more conscious state, observing what’s going on at the surface, then going back down if all is well.</p> <p>Some evidence suggests “fever dreams” are far less common than we might expect. We actually experience <a href="https://www.frontiersin.org/articles/10.3389/fpsyg.2020.00053/full">far less REM sleep</a> when we have a fever – though the dreams we do have tend to be <a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3830719/">darker in tone and more unusual</a>.</p> <p>Spending less time in REM sleep when we’re feverish might happen because we are far less capable of regulating our body temperature in this stage of sleep. To protect us, our brain tries to regulate our temperature by “skipping” this sleep stage. We tend to have fewer dreams when the weather is hot <a href="https://www.tandfonline.com/doi/abs/10.1080/23744731.2020.1756664">for the same reason</a>.</p> <h2>A deep-cleaning system for the brain</h2> <p>REM sleep is important for ensuring our brain is working as it should, as indicated by studies using <a href="https://www.cell.com/current-biology/pdf/S0960-9822(17)31329-5.pdf">electoencephalography</a>, which measures brain activity.</p> <p>In the same way deep sleep helps the body restore its physical capacity, dream sleep “<a href="https://www.cell.com/current-biology/pdf/S0960-9822(17)31329-5.pdf">back-flushes</a>” our neural circuits. At the molecular level, the chemicals that underpin our thinking are bent out of shape by the day’s cognitive activity. Deep sleep is when those chemicals are returned to their unused shape. The brain is “<a href="https://www.science.org/doi/abs/10.1126/science.1241224">washed</a>” with cerebrospinal fluid, controlled by the <a href="https://theconversation.com/on-your-back-side-face-down-mice-show-how-we-sleep-may-trigger-or-protect-our-brain-from-diseases-like-als-181954">glymphatic system</a>.</p> <p>At the next level, dream sleep “tidies up” our recent memories and feelings. During <a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC534695/">REM sleep</a>, our brains consolidate procedural memories (of how to do tasks) and emotions. <a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC534695/">Non-REM sleep</a>, where we typically expect fewer dreams, is important for the consolidation of episodic memories (events from your life).</p> <p>As our night’s sleep progresses, we produce more cortisol - the <a href="https://psycnet.apa.org/record/2005-01907-021">stress hormone</a>. It is thought the amount of cortisol present can impact the type of memories we are consolidating and potentially the types of dreams we have. This means the dreams we have later in the night may be <a href="https://learnmem.cshlp.org/content/11/6/671.full.pdf">more fragmented or bizarre</a>.</p> <p>Both kinds of sleep help <a href="https://www.researchgate.net/profile/Jb-Eichenlaub/publication/313545620_Daily_Life_Experiences_in_Dreams_and_Sleep-Dependent_Memory_Consolidation/links/5c532b0ba6fdccd6b5d76270/Daily-Life-Experiences-in-Dreams-and-Sleep-Dependent-Memory-Consolidation.pdf?ref=nepopularna.org">consolidate</a> the useful brain activity of the day. The brain also discards less important information.</p> <h2>Random thoughts, rearranged feelings</h2> <p>This filing and discarding of the day’s activities is going on while we are sleeping. That’s why we often dream about things that happen <a href="https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0264574">during the day</a>.</p> <p>Sometimes when we’re rearranging the thoughts and feelings to go in the “<a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3921176/">bin</a>” during sleep, our level of consciousness allows us to experience awareness. Random thoughts and feelings end up all jumbled together in weird and wonderful ways. Our awareness of this process may explain the bizarre nature of some of our dreams. Our daytime experiences can also fuel nightmares or anxiety-filled dreams after a <a href="https://www.sleepfoundation.org/dreams/how-trauma-can-affect-dreams">traumatic event</a>.</p> <p>Some dreams appear to <a href="https://rai.onlinelibrary.wiley.com/doi/pdfdirect/10.1111/j.1467-9655.2010.01668.x">foretell the future or carry potent symbolism</a>. In many societies dreams are believed to be a window into an <a href="https://digitalcommons.ciis.edu/cgi/viewcontent.cgi?article=1050&amp;context=ijts-transpersonalstudies">alternate reality</a> where we can envisage what is possible.</p> <h2>What does it all mean?</h2> <p>Our scientific understanding of the thermoregulatory, molecular and basic neural aspects of dreaming sleep is <a href="https://www.nature.com/articles/nrn2716">good</a>. But the psychological and spiritual aspects of dreaming remain largely hidden.</p> <p>Perhaps our brains are wired to try and make sense of things. Human societies have always interpreted the random – birds wheeling, tea leaves and the planets – and looked for <a href="https://brill.com/display/book/edcoll/9789047407966/B9789047407966-s003.xml">meaning</a>. Nearly every human society has regarded dreams as more than just random neural firing.</p> <p>And the history of science tells us some things once thought to be magic can later be understood and harnessed – for better or worse.<!-- Below is The Conversation's page counter tag. Please DO NOT REMOVE. --><img style="border: none !important; box-shadow: none !important; margin: 0 !important; max-height: 1px !important; max-width: 1px !important; min-height: 1px !important; min-width: 1px !important; opacity: 0 !important; outline: none !important; padding: 0 !important;" src="https://counter.theconversation.com/content/210901/count.gif?distributor=republish-lightbox-basic" alt="The Conversation" width="1" height="1" /><!-- End of code. If you don't see any code above, please get new code from the Advanced tab after you click the republish button. The page counter does not collect any personal data. More info: https://theconversation.com/republishing-guidelines --></p> <p><a href="https://theconversation.com/profiles/drew-dawson-13517"><em>Drew Dawson</em></a><em>, Director, Appleton Institute, <a href="https://theconversation.com/institutions/cquniversity-australia-2140">CQUniversity Australia</a> and <a href="https://theconversation.com/profiles/madeline-sprajcer-1315489">Madeline Sprajcer</a>, Lecturer in Psychology, <a href="https://theconversation.com/institutions/cquniversity-australia-2140">CQUniversity Australia</a></em></p> <p><em>Image credits: Shutterstock</em></p> <p><em>This article is republished from <a href="https://theconversation.com">The Conversation</a> under a Creative Commons license. Read the <a href="https://theconversation.com/the-science-of-dreams-and-nightmares-what-is-going-on-in-our-brains-while-were-sleeping-210901">original article</a>.</em></p>

Mind

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If anxiety is in my brain, why is my heart pounding? A psychiatrist explains the neuroscience and physiology of fear

<p><em><a href="https://theconversation.com/profiles/arash-javanbakht-416594">Arash Javanbakht</a>, <a href="https://theconversation.com/institutions/wayne-state-university-989">Wayne State University</a></em></p> <p>Heart in your throat. Butterflies in your stomach. Bad gut feeling. These are all phrases many people use to describe fear and anxiety. You have likely felt anxiety inside your chest or stomach, and your brain usually doesn’t hurt when you’re scared. Many cultures tie cowardice and bravery more <a href="https://afosa.org/the-meaning-of-heart-qalb-in-quran/">to the heart</a> <a href="https://byustudies.byu.edu/article/bowels-of-mercy/">or the guts</a> than to the brain.</p> <p>But science has traditionally seen the brain as the birthplace and processing site of fear and anxiety. Then why and how do you feel these emotions in other parts of your body?</p> <p>I am a <a href="https://scholar.google.com/citations?user=UDytFmIAAAAJ&amp;hl=en">psychiatrist and neuroscientist</a> who researches and treats fear and anxiety. In my book “<a href="https://rowman.com/ISBN/9781538170380/Afraid-Understanding-the-Purpose-of-Fear-and-Harnessing-the-Power-of-Anxiety">Afraid,</a>” I explain how fear works in the brain and the body and what too much anxiety does to the body. Research confirms that while emotions do originate in your brain, it’s your body that carries out the orders.</p> <h2>Fear and the brain</h2> <p>While your brain evolved to save you from a falling rock or speeding predator, the anxieties of modern life are often a lot more abstract. Fifty-thousand years ago, being rejected by your tribe could mean death, but not doing a great job on a public speech at school or at work doesn’t have the same consequences. Your brain, however, <a href="https://doi.org/10.1006/nimg.2002.1179">might not know the difference</a>.</p> <p>There are a few key areas of the brain that are heavily involved in processing fear.</p> <p>When you perceive something as dangerous, whether it’s a gun pointed at you or a group of people looking unhappily at you, these sensory inputs are first relayed to <a href="https://doi.org/10.1038%2Fnpp.2009.121">the amygdala</a>. This small, almond-shaped area of the brain located near your ears detects salience, or the emotional relevance of a situation and how to react to it. When you see something, it determines whether you should eat it, attack it, run away from it or have sex with it.</p> <p><a href="https://theconversation.com/the-science-of-fright-why-we-love-to-be-scared-85885">Threat detection</a> is a vital part of this process, and it has to be fast. Early humans did not have much time to think when a lion was lunging toward them. They had to act quickly. For this reason, the amygdala evolved to bypass brain areas involved in logical thinking and can directly engage physical responses. For example, seeing an angry face on a computer screen can immediately trigger a <a href="https://doi.org/10.1006/nimg.2002.1179">detectable response from the amygdala</a> without the viewer even being aware of this reaction.</p> <figure><iframe src="https://www.youtube.com/embed/xoU9tw6Jgyw?wmode=transparent&amp;start=0" width="440" height="260" frameborder="0" allowfullscreen="allowfullscreen"></iframe><figcaption><span class="caption">In response to a looming threat, mammals often fight, flee or freeze.</span></figcaption></figure> <p><a href="https://doi.org/10.1038/npp.2009.83">The hippocampus</a> is near and tightly connected to the amygdala. It’s involved in memorizing what is safe and what is dangerous, especially in relation to the environment – it puts fear in context. For example, seeing an angry lion in the zoo and in the Sahara both trigger a fear response in the amygdala. But the hippocampus steps in and blocks this response when you’re at the zoo because you aren’t in danger.</p> <p>The <a href="https://doi.org/10.1176/appi.ajp.2016.16030353">prefrontal cortex</a>, located above your eyes, is mostly involved in the cognitive and social aspects of fear processing. For example, you might be scared of a snake until you read a sign that the snake is nonpoisonous or the owner tells you it’s their friendly pet.</p> <p>Although the prefrontal cortex is usually seen as the part of the brain that regulates emotions, it can also teach you fear based on your social environment. For example, you might feel neutral about a meeting with your boss but immediately feel nervous when a colleague tells you about rumors of layoffs. Many <a href="https://theconversation.com/trump-the-politics-of-fear-and-racism-how-our-brains-can-be-manipulated-to-tribalism-139811">prejudices like racism</a> are rooted in learning fear through tribalism.</p> <h2>Fear and the rest of the body</h2> <p>If your brain decides that a fear response is justified in a particular situation, it activates a <a href="https://doi.org/10.1093/med/9780190259440.003.0019">cascade of neuronal and hormonal pathways</a> to prepare you for immediate action. Some of the fight-or-flight response – like heightened attention and threat detection – takes place in the brain. But the body is where most of the action happens.</p> <p>Several pathways prepare different body systems for intense physical action. The <a href="https://doi.org/10.3389/fnins.2014.00043">motor cortex</a> of the brain sends rapid signals to your muscles to prepare them for quick and forceful movements. These include muscles in the chest and stomach that help protect vital organs in those areas. That might contribute to a feeling of tightness in your chest and stomach in stressful conditions.</p> <figure><iframe src="https://www.youtube.com/embed/0IDgBlCHVsA?wmode=transparent&amp;start=0" width="440" height="260" frameborder="0" allowfullscreen="allowfullscreen"></iframe><figcaption><span class="caption">Your sympathetic nervous system is involved in regulating stress.</span></figcaption></figure> <p>The <a href="https://www.ncbi.nlm.nih.gov/books/NBK542195/">sympathetic nervous system</a> is the gas pedal that speeds up the systems involved in fight or flight. Sympathetic neurons are spread throughout the body and are especially dense in places like the heart, lungs and intestines. These neurons trigger the adrenal gland to release hormones like adrenaline that travel through the blood to reach those organs and increase the rate at which they undergo the fear response.</p> <p>To assure sufficient blood supply to your muscles when they’re in high demand, signals from the sympathetic nervous system increase the rate your heart beats and the force with which it contracts. You feel both increased heart rate and contraction force in your chest, which is why you may connect the feeling of intense emotions to your heart.</p> <p>In your lungs, signals from the sympathetic nervous system dilate airways and often increase your breathing rate and depth. Sometimes this results in a feeling of <a href="https://theconversation.com/pain-and-anxiety-are-linked-to-breathing-in-mouse-brains-suggesting-a-potential-target-to-prevent-opioid-overdose-deaths-174187">shortness of breath</a>.</p> <p>As digestion is the last priority during a fight-or-flight situation, sympathetic activation slows down your gut and reduces blood flow to your stomach to save oxygen and nutrients for more vital organs like the heart and the brain. These changes to your gastrointestinal system can be perceived as the discomfort linked to fear and anxiety.</p> <h2>It all goes back to the brain</h2> <p>All bodily sensations, including those visceral feelings from your chest and stomach, are relayed back to the brain through the pathways <a href="https://www.ncbi.nlm.nih.gov/books/NBK555915/">via the spinal cord</a>. Your already anxious and highly alert brain then processes these signals at both conscious and unconscious levels.</p> <p><a href="https://doi.org/10.1176/appi.ajp.2016.16030353">The insula</a> is a part of the brain specifically involved in conscious awareness of your emotions, pain and bodily sensations. The <a href="https://doi.org/10.1038%2Fs41598-019-52776-4">prefrontal cortex</a> also engages in self-awareness, especially by labeling and naming these physical sensations, like feeling tightness or pain in your stomach, and attributing cognitive value to them, like “this is fine and will go away” or “this is terrible and I am dying.” These physical sensations can sometimes create a loop of increasing anxiety as they make the brain feel more scared of the situation because of the turmoil it senses in the body.</p> <p>Although the feelings of fear and anxiety start in your brain, you also feel them in your body because your brain alters your bodily functions. Emotions take place in both your body and your brain, but you become aware of their existence with your brain. As the rapper Eminem recounted in his song “Lose Yourself,” the reason his palms were sweaty, his knees weak and his arms heavy was because his brain was nervous.<!-- Below is The Conversation's page counter tag. Please DO NOT REMOVE. --><img style="border: none !important; box-shadow: none !important; margin: 0 !important; max-height: 1px !important; max-width: 1px !important; min-height: 1px !important; min-width: 1px !important; opacity: 0 !important; outline: none !important; padding: 0 !important;" src="https://counter.theconversation.com/content/210871/count.gif?distributor=republish-lightbox-basic" alt="The Conversation" width="1" height="1" /><!-- End of code. If you don't see any code above, please get new code from the Advanced tab after you click the republish button. The page counter does not collect any personal data. More info: https://theconversation.com/republishing-guidelines --></p> <p><a href="https://theconversation.com/profiles/arash-javanbakht-416594"><em>Arash Javanbakht</em></a><em>, Associate Professor of Psychiatry, <a href="https://theconversation.com/institutions/wayne-state-university-989">Wayne State University</a></em></p> <p><em>Image credits: Getty Images</em></p> <p><em>This article is republished from <a href="https://theconversation.com">The Conversation</a> under a Creative Commons license. Read the <a href="https://theconversation.com/if-anxiety-is-in-my-brain-why-is-my-heart-pounding-a-psychiatrist-explains-the-neuroscience-and-physiology-of-fear-210871">original article</a>.</em></p>

Body

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Tourist accused of causing over $8,000 in damages to iconic Roman statue

<p>A 22-year-old German tourist has been accused of causing around €5,000 (A$8,400) in damages to the 16th-century Fountain of Neptune in the Piazza della Signoria, Italy. </p> <p>Surveillance footage obtained by the police allegedly show the tourist - who has not been named - climbing over the protective barrier around the monument in the early hours of Monday morning as he posed for a photo on the statue. </p> <p>His two friends, who stood outside of the barrier, took the photos of him and they all fled the scene when the alarm went off, according to city authorities.</p> <p>"According to the investigators' reconstruction, after 1 o'clock this morning the tourist, in Piazza della Signoria with two other friends, climbed over the fence of the Neptune Fountain and climbed onto the edge of the pool," the statement read. </p> <p>"With a jump he then climbed onto the horse's leg, reaching the base of the carriage and, after having some photos taken by his friends, he climbed down," they added.</p> <p>"During the descent he placed his foot again on the hoof, damaging it. As soon as the alarm went off, however, the young man had already managed to escape with the two others." </p> <p>The tourist will be charged under the city penal code that prohibits the "destruction, dispersion, deterioration, disfigurement, soiling or illicit use of cultural or landscape assets."</p> <p>He has been detained in Florence and could be fined and banned from entering the city if convicted. </p> <p>Image:<em> X (formerly Twitter)</em></p>

Travel Trouble

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These 8 food and drink favourites are bad for your brain

<p><strong>Bad foods for your brain</strong></p> <p>Following a healthy diet is essential to maintaining optimal brain health. Avocados and fatty fish; bone broth, berries and broccoli – they’re all brain-boosting superstars. But there are plenty of foods that have the opposite effect and can sap your smarts, affecting your memory and mood. Therefore, it’s important to cut or reduce the following food from your diet to mitigate their effects.</p> <p><strong>Fried foods</strong></p> <p>Fried chicken and French fries won’t just widen your waistline, they are also bad for your brain. In a study published in 2016 in the Journal of Nutritional Science, people who ate diets high in fried foods scored poorly on cognitive tests that evaluated learning, memory and brain function. Conversely, those who ate more plant-based foods scored higher.</p> <p>“Scientists think it may have something to do with inflammation and reduction in brain tissue size,” says Kristin Kirkpatrick, co-author of Skinny Liver. “When you look at aspects of one of the great brain studies – the MIND diet – it clearly shows which foods may cause or reduce inflammation in the brain. Fried foods are on the NO list, while berries, olive oil, whole grains and food containing omega 3 are on the YES list.”</p> <p><strong>Sugar-sweetened beverages</strong></p> <p>You probably know to stay away from soft drinks. But you should also beware of fruit juice, energy drinks and sweet tea. Why, you ask? The same reason soft drink is among the bad foods for your brain: sugar.</p> <p>“High amounts of sugar causes neurological damage” because it triggers inflammation, says the Academy of Nutrition and Dietetics’ Wesley Delbridge. A study published in 2017 in Alzheimer’s &amp; Dementia backs that up. Researchers found that people who regularly consume sugary drinks are more likely to have poorer memory, smaller overall brain volume, and a significantly smaller hippocampus – the part of the brain important for learning and memory – than those who don’t.</p> <p>Instead of drinking fruit juice or sweet tea high in sugar, try sweetening water or tea with slices of oranges, lemons, or limes.</p> <p><strong>Refined carbs</strong></p> <p>White rice, white bread, white pasta and other processed food with a high glycemic index don’t just cause major spikes in blood sugar, they also rank with the ‘bad foods for your brain’. Specifically, these foods can have a negative effect on your mental health. A study, published in 2015 in The American Journal of Clinical Nutrition found that food with a high glycemic index can raise the risk of depression in post-menopausal women. Women who ate more lactose, fibre, fruit and vegetables, on the other hand, showed a significant decrease in symptoms of depression.</p> <p>Swap the white carbs for complex carbs like whole wheat bread, brown rice, quinoa, barley, and farro. All of these contain fibre, which nurtures your gut bacteria and regulates inflammation – all good things for your brain health.</p> <p><strong>Excess alcohol</strong></p> <p>There is a sweet spot for alcohol consumption, according to neurologist Dr David Perlmutter and author of Grain Brain: The Surprising Truth about Wheat, Carbs, and Sugar. While the occasional glass of red wine is okay, drinking in excess can be toxic to your brain function, no matter your age. Research, including a study published in 2017 in the peer-reviewed medical trade journal BMJ, found that moderate drinking can damage the brain. The hippocampus is particularly vulnerable.</p> <p>To protect your brain, limit alcohol consumption to no more than one standard drink per day for women and two per day for men. According to Australia’s national alcohol guidelines, one standard drink is defined as containing 10 grams of alcohol. </p> <p><strong>Artificially sweetened beverages</strong></p> <p>Instead of a sugar-sweetened beverage, maybe you turn to the occasional diet soft drink. But make a habit of it and you could be upping your risk of dementia and stroke, suggests a study published in 2017 in Stroke. Researchers found that participants who drank diet drinks daily were almost three times as likely to have a stroke or develop dementia when compared to those who didn’t.</p> <p>“We seek out diet soft drinks for its sweet delivery of liquid,” says Kirkpatrick. “That sweet taste remains on our taste buds, making us crave more.”</p> <p>To kick the habit, she suggests going cold turkey. “Eliminate all sources of sweet from the taste buds to retrain the brain not to want it in the first place,” she says. “Sprucing up water with lemons, limes or berries, or having flavoured seltzer without added sugar can help, as well.”</p> <p><strong>Processed meats </strong></p> <p>If you like to eat processed meats, you may run a greater risk of developing dementia, suggests an April 2020 study published in Neurology. Although the study does not prove cause and effect, the researchers found that dementia was more common among participants who ate highly processed meats, such as sausages, cured meats and pâté. People without dementia were more likely to eat a diverse diet that included fruit, vegetables, seafood and poultry, according to the findings.</p> <p>Highly processed foods are most likely the primary cause of results linked to the reduction in brain tissue size and inflammation, which impacts brain health, says Kirkpatrick.</p> <p><strong>Fast food </strong></p> <p>For starters, the high levels of saturated fat found in greasy burgers and fries can make it harder to fight off Alzheimer-causing plaque. Plus, the level of sodium found in the average fast-food fix can cause brain fog. How so?  High blood pressure, often brought on by eating too many salty foods, can restrict blood to the brain and negatively impair focus, organisational skills and memory, suggests a review of studies published in 2016 in Hypertension.</p> <p>To break a fast food habit, Kirkpatrick suggests this trick: “Start with altering what you order,” she says. “Avoid fried options and opt for more whole grains and plants.” Then reduce the number of days you buy fast food by half.</p> <p><strong>Tuna</strong></p> <p>While the occasional tuna sandwich is no big deal, you might want to think twice before making it your go-to lunch. That’s because tuna – as well as swordfish, shark (flake), bill fish and deep sea perch – has higher levels of mercury than many other types of seafood. A study published in Integrative Medicine shows that people with high levels of the heavy metal in their bloodstream had a 5% drop in cognitive function.</p> <p>But you don’t have to banish seafood from your plate forever. Advice from Food Standards Australia New Zealand (which reflects the fish we eat in our region and its mercury content) recommends 2-3 serves per week of fish and seafood, including canned or fresh tuna (one serve equals 150g), except for fish such as orange roughy (deep sea perch), catfish, shark (flake) or billfish (swordfish/marlin), which you should only consume 1 serve per week and no other fish that week.</p> <p>Try swapping these varieties of fish for omega-3-rich sources such as wild salmon and lake trout, which have been associated with better brain health, says Kirkpatrick.</p> <p><em>Image credits: Getty Images</em></p> <p><em>This article originally appeared on <a href="https://www.readersdigest.com.au/food-home-garden/the-8-worst-foods-for-your-brain" target="_blank" rel="noopener">Reader's Digest</a>. </em></p>

Food & Wine

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Finding a live brain worm is rare. 4 ways to protect yourself from more common parasites

<p><em><a href="https://theconversation.com/profiles/vincent-ho-141549">Vincent Ho</a>, <a href="https://theconversation.com/institutions/western-sydney-university-1092">Western Sydney University</a></em></p> <p><a href="https://www.theguardian.com/australia-news/2023/aug/28/live-worm-living-womans-brain-australia-depression-forgetfulness">News reports</a> this morning describe how shocked doctors removed a live worm from a woman’s brain in a Canberra hospital last year. The woman had previously been admitted to hospital with stomach symptoms, dry cough and night sweats and months later experienced depression and forgetfulness that led to a brain scan.</p> <p>In the <a href="https://wwwnc.cdc.gov/eid/article/29/9/23-0351_article">case study</a> published in Emerging Infectious Diseases journal, doctors describe removing the live 8cm-long nematode (roundworm) from the brain of the 64-year-old woman who was immunosuppressed. The worm was identified as <em>O. robertsi</em> which is native to Australia, where it lives on carpet pythons. The woman may have come into contact with worm eggs via snake faeces while foraging for Warrigal greens to eat.</p> <p>It’s important to note this is an extremely rare event and headlines about brain worms can be alarming. But there are more common parasites which can infect your body and brain. And there are ways you can minimise your risks of being infected with one.</p> <h2>Common parasites and how they get in</h2> <p>Parasitic infection is extremely common. Arguably the most widespread type is pinworm (<em>Enterobius vermicularis</em> also called threadworm), which is thought to be present in <a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6522669/">over a billion people</a> worldwide, especially children. Pinworms grow to around 1cm in length and are specific to human hosts. They cause intense bottom itching and get passed from person-to-person. It’s a myth that you can get it from pets.</p> <p><a href="https://www.cdc.gov/parasites/giardia/pathogen.html#:%7E:text=Giardia%20duodenalis%20is%20a%20protozoan,Giard%20of%20Paris%20and%20Dr.">Giardia</a> (<em>Giardia duodenalis</em>) is also very common and can contaminate food, water and surfaces. This water-borne parasite is associated with poor sanitation and causes stomach symptoms like diarrhoea, cramps, bloating, nausea and fatigue. Giardia cysts (little sacs of immature parasite) spread disease and are passed out in faeces, where they can remain viable in the environment for months before being consumed by someone else. They can also be ingested via foods (such as sheep meat) that is raw or undercooked.</p> <p><a href="https://www.cdc.gov/dpdx/hookworm/index.html">Two types</a> of hookworm – <em>Necator americanis</em> and <em>Ancylostoma duadonale</em> – are found in soil. Only <em>Ancylostoma duodenale</em> is an issue in Australia and is typically found in <a href="https://www.cdc.gov/dpdx/hookworm/index.html">remote communities</a>.</p> <p>When a person is infected (usually via barefeet or contaminated footwear) these worms enter the bloodstream and then hit the lungs. From the bronchi in the upper lungs, they are swallowed with secretions. Once in the gut and small bowel they can <a href="https://www.who.int/news-room/fact-sheets/detail/soil-transmitted-helminth-infections#:%7E:text=Transmission,these%20eggs%20contaminate%20the%20soil.">cause anaemia</a> (low iron). This is because they are consuming nutrients and affecting iron absorption. They also release an anticoagulant that stops the human host’s blood clotting and causes tiny amounts of blood loss.</p> <p>Fortunately, these very common parasites do not infect the brain.</p> <p>Across the world, it’s estimated <a href="https://pubmed.ncbi.nlm.nih.gov/22491772/">30–50% of people</a> are infected with <em>Toxoplasma</em>. Most people will be asymptomatic but many carry the <a href="https://theconversation.com/one-in-three-people-are-infected-with-toxoplasma-parasite-and-the-clue-could-be-in-our-eyes-182418">signs of infection</a>.</p> <p>The parasites can remain in the body for years as tiny tissue cysts. These cysts can be found in brain, heart and muscle. Infants can be born with serious eye or brain damage if their mothers are infected during pregnancy. People with compromised immunity – such as from AIDS or cancer treatment – are also at risk of illness from infection via pet cats or uncooked meat.</p> <h2>Then there are tapeworms and amoebas</h2> <p>Tapeworms can infect different parts of the body including the brain. This is called <a href="https://www.cdc.gov/parasites/resources/pdf/npis_in_us_neurocysticercosis.pdf">neurocysticercosis</a> and is the leading cause of epilepsy worldwide. Neurocysticercosis is uncommon in the Western world and infection is usually via eating pork that is uncooked or prepared by someone who is infected with tapeworm (<em>Taenia solium</em>). It is more likely in locations where pigs have contact with human faeces via sewerage or waterways.</p> <figure class="align-right zoomable"><figcaption></figcaption></figure> <p>Tapeworm larvae can infect muscle and soft tissue. Brain tissue can provide a home for larvae because it is soft and easy to get to via blood vessels. Brain infection can cause headaches, dizziness, seizures, cognitive impairment and even dementia, due to an increase in <a href="https://www.cdc.gov/parasites/cysticercosis/gen_info/faqs.html">cerebral spinal fluid pressure</a>.</p> <p><em><a href="https://www.cdc.gov/parasites/naegleria/general.html">Naegleria fowleri</a></em> is an amoeba found in lakes, rivers and springs in warm climates including <a href="https://www.sahealth.sa.gov.au/wps/wcm/connect/public+content/sa+health+internet/public+health/water+quality/naegleria+fowleri#:%7E:text=How%20common%20are%20Naegleria%20fowleri,frequently%20found%20in%20the%20environment.">in Australia</a>. People swimming in infected waters can have the parasite enter their body through the nose. It then travels to the brain and destroys brain tissue. The condition is <a href="https://www.cdc.gov/parasites/naegleria/general.html#:%7E:text=Top%20of%20Page-,What%20is%20the%20death%20rate%20for%20an%20infected%20person%20who,States%20from%201962%20to%202022.">almost always fatal</a>.</p> <h2>Yikes! 4 ways to avoid parasitic infection</h2> <p>That all sounds very scary. And we know being infected by a snake parasite is very rare – finding one alive in someone’s brain is even rarer. But parasites are all around us. To minimise your risk of infection you can:</p> <p><strong>1.</strong> avoid undercooked or raw pork. Freezing meat first may reduce risks (though home freezers <a href="https://www.cdc.gov/parasites/trichinellosis/prevent.html">may not get cold enough</a>) and it must be cooked to a <a href="https://www.sciencedirect.com/science/article/pii/S0924224418301560#:%7E:text=and%20time%20conditions.-,Cooking%20at%20core%20temperature%2060%E2%80%9375%20%C2%B0C%20for%2015,relied%20upon%20in%20home%20situations.">high internal temperature</a>. Avoid pork if you are travelling in places with poor sanitation</p> <p><strong>2.</strong> avoid jumping or diving into warm fresh bodies of water, especially if they are known to carry <em>Naegleria fowleri</em>. Although only a <a href="https://www.cdc.gov/parasites/naegleria/graphs.html">handful of cases</a> are reported each year, you should assume it’s present</p> <p><strong>3.</strong> practise good <a href="https://www.cdc.gov/handwashing/when-how-handwashing.html#:%7E:text=Follow%20Five%20Steps%20to%20Wash%20Your%20Hands%20the%20Right%20Way&amp;text=Wet%20your%20hands%20with%20clean,for%20at%20least%2020%20seconds.">hand hygiene</a> to reduce the risk of rare and common infections. That means washing hands thoroughly and often, using soap, scrubbing for at least 20 seconds, rinsing and drying well. Clip and clean under fingernails regularly</p> <p><strong>4.</strong> to avoid soil-borne parasites wear shoes outside, especially in rural and remote regions, wash shoes and leave them outside.<!-- Below is The Conversation's page counter tag. Please DO NOT REMOVE. --><img style="border: none !important; box-shadow: none !important; margin: 0 !important; max-height: 1px !important; max-width: 1px !important; min-height: 1px !important; min-width: 1px !important; opacity: 0 !important; outline: none !important; padding: 0 !important;" src="https://counter.theconversation.com/content/212437/count.gif?distributor=republish-lightbox-basic" alt="The Conversation" width="1" height="1" /><!-- End of code. If you don't see any code above, please get new code from the Advanced tab after you click the republish button. The page counter does not collect any personal data. More info: https://theconversation.com/republishing-guidelines --></p> <p><em><a href="https://theconversation.com/profiles/vincent-ho-141549">Vincent Ho</a>, Associate Professor and clinical academic gastroenterologist, <a href="https://theconversation.com/institutions/western-sydney-university-1092">Western Sydney University</a></em></p> <p><em>Image credits: Canberra Health </em></p> <p><em>This article is republished from <a href="https://theconversation.com">The Conversation</a> under a Creative Commons license. Read the <a href="https://theconversation.com/finding-a-live-brain-worm-is-rare-4-ways-to-protect-yourself-from-more-common-parasites-212437">original article</a>.</em></p>

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Australian researchers confirm world’s first case of dementia linked to repetitive brain trauma in a female athlete

<p><em><a href="https://theconversation.com/profiles/stephen-townsend-501829">Stephen Townsend</a>, <a href="https://theconversation.com/institutions/the-university-of-queensland-805">The University of Queensland</a>; <a href="https://theconversation.com/profiles/alan-pearce-734804">Alan Pearce</a>, <a href="https://theconversation.com/institutions/la-trobe-university-842">La Trobe University</a>, and <a href="https://theconversation.com/profiles/rebecca-olive-944640">Rebecca Olive</a>, <a href="https://theconversation.com/institutions/rmit-university-1063">RMIT University</a></em></p> <p>Researchers at the <a href="https://www.brainbank.org.au/">Australian Sports Brain Bank</a> have today reported the world’s first diagnosis of chronic traumatic encephalopathy (CTE) in a <a href="https://rdcu.be/dfQiz">female athlete</a>.</p> <p>With the consent of her family, the diagnosis was made on the brain of Heather Anderson, a 28-year-old AFLW athlete <a href="https://www.abc.net.au/news/2022-11-14/adelaide-aflw-premiership-player-heather-anderson-dies-aged-28/101653188">who died</a> last November. Heather’s family donated her brain to the Australian Sports Brain Bank hoping to better understand why she died.</p> <p>The findings, which Professor Alan Pearce co-authored with the Australian Sports Brain Bank, raise questions about how a lifetime of contact sport may have contributed to her death. They come as Australia’s <a href="https://www.aph.gov.au/Parliamentary_Business/Committees/Senate/Community_Affairs/Headtraumainsport">Senate inquiry</a> works on its report into concussions and repeated head trauma in contact sport, due in August.</p> <p>Given how hard women have fought to participate in football codes and contact sports in recent years, this diagnosis has major implications for women’s sport in Australia. It also highlights the significant lack of research about women athletes in sport science and medicine.</p> <h2>What is chronic traumatic encephalopathy?</h2> <p><a href="https://www.mayoclinic.org/diseases-conditions/chronic-traumatic-encephalopathy/symptoms-causes/syc-20370921">CTE</a> is a devastating form of dementia which causes a decline in brain functioning and increased risk of mental illness. It is increasingly associated with athletes who play contact sports, such as football, boxing and martial arts.</p> <p>It is incurable and can only be <a href="https://www.brainbank.org.au/cte-diagnosis/">diagnosed post-mortem</a>. Recently, a number of high-profile former Australian footballers were found to have been suffering from CTE when they died, including former AFL stars <a href="https://www.abc.net.au/news/2023-04-26/danny-frawley-family-urges-afl-to-act-on-cte-concussion/102269648">Danny Frawley</a> and <a href="https://www.abc.net.au/news/2022-08-25/brain-disease-killed-shane-tuck-not-mental-health-says-sister/101362740">Shane Tuck</a>, and former NRL player and coach <a href="https://www.abc.net.au/news/2022-10-22/qld-paul-green-brain-scans-reveal-brain-disease-cte-diagnosis/101566032">Paul Green</a>.</p> <blockquote class="twitter-tweet"> <p dir="ltr" lang="en">Adelaide AFLW premiership player Heather Anderson dies aged 28 <a href="https://t.co/ihy2i9UcRl">https://t.co/ihy2i9UcRl</a></p> <p>— ABC News (@abcnews) <a href="https://twitter.com/abcnews/status/1592079585201381377?ref_src=twsrc%5Etfw">November 14, 2022</a></p></blockquote> <p>Concussions in contact sports have long been associated with long-term neurodegeneration in <a href="https://www.frontiersin.org/articles/10.3389/fspor.2021.676463/full">Australia</a> and <a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3987576/">internationally</a>. While the public and researchers are rightly concerned about serious concussions, a study published last month in <a href="https://urldefense.com/v3/__https:/www.nature.com/articles/s41467-023-39183-0__;!!PDiH4ENfjr2_Jw!FvAmUDcX-ESwwl8nG_BNNkRyB2J4TBq1oXkBTE1bBcdRGEQTl4u7qmgGsLguHpGNlFpWkz-SjKg3HGwdNYxIfEWW9U6ifytx%24">Nature Communications</a> confirmed that repetitive brain trauma over time – even seemingly mild head knocks or whiplash – is the strongest predictor for an athlete developing CTE. Athletes with long careers in contact sport are at particular risk, especially if they play from an early age.</p> <h2>A sporting life</h2> <p>Heather Anderson began playing rugby league at age five before transferring to Australian rules football in her early teens. She played representative football in the Australian Capital Territory and Northern Territory before being drafted into the inaugural season of the AFLW in 2017.</p> <p>Anderson played a single season with the <a href="https://crowshistory.afc.com.au/aflw-players/heather-anderson#:%7E:text=Biography&amp;text=An%20army%20medic%2C%20Heather%20Anderson,year%20and%20starred%20for%20Waratah.">Adelaide Crows</a>, during which she won a premiership and suffered a career-ending shoulder injury. She then returned to her role as a medic with the Australian Army, a physical career which also carries a <a href="https://www.defence.gov.au/adf-members-families/health-well-being/programs-initiatives/military-health-outcomes-program">heightened risk of brain injury</a>.</p> <p>Anderson’s family donated her brain in the hope of knowing whether a lifetime of exposure to repetitive head trauma contributed to her death.</p> <h2>Was this diagnosis expected?</h2> <p>Concussion researcher Anne McKee predicted earlier this year it was a <a href="https://www.1news.co.nz/2023/02/20/its-coming-experts-worried-about-female-athlete-brain-injuries/">matter of time</a> before CTE was found in the brain of a woman athlete.</p> <p>The Australian Sports Brain Bank team believe Anderson is a “<a href="https://www.ncbi.nlm.nih.gov/books/NBK564388/">sentinel case</a>” we can learn from. She is the first female athlete diagnosed with CTE, but she will not be the last.</p> <p>Although Australian women have historically been excluded from the sports most associated with repeated head injuries, this is changing. In 2022, there were almost one million women and girls playing some form of <a href="https://www.clearinghouseforsport.gov.au/kb/women-in-sport">contact sport</a> in Australia. As women’s participation in contact sport continues to grow, so too does their risk of repetitive brain trauma.</p> <h2>Are women more prone to CTE than men?</h2> <p>There is emerging evidence that women are at significantly higher risk of mild traumatic brain injury (concussion) and may suffer more severe symptoms.</p> <p>Concussion alone does not cause CTE, but an athlete’s number of concussions is a reliable indicator of their cumulative exposure to brain trauma, which is the biggest predictor of CTE.</p> <p>While knowledge on the topic is still developing, researchers <a href="https://www.nature.com/articles/d41586-021-02089-2">propose a mix of physiological and social explanations</a> for women’s increased concussion risk. These include "[…] differences in the microstructure of the brain to the influence of hormones, coaching regimes, players’ level of experience and the management of injuries."</p> <p>More research is needed to understand sporting brain injuries specifically in women and girls. Given their growth in participation and the enhanced risks they face in sport, it is concerning that women and girls are <a href="https://bjsm.bmj.com/content/56/17/981">underrepresented</a> in concussion research.</p> <p>This is representative of a <a href="https://journals-humankinetics-com.ap1.proxy.openathens.net/view/journals/wspaj/29/2/article-p146.xml">broader trend</a> in sport and exercise science research to exclude women from studies because their bodies are perceived as <a href="https://link.springer.com/article/10.1007/s40279-021-01435-8">more complex</a> than men’s and thus more difficult to accommodate in testing.</p> <h2>A disease that does not discriminate</h2> <p>This world-first report of CTE in a female athlete is proof the disease does not discriminate and lends urgency to calls for <a href="https://theconversation.com/sports-concussions-affect-men-and-women-differently-female-athletes-need-more-attention-in-brain-research-160097">greater representation</a> of women in brain injury studies.</p> <p>Efforts to reduce concussion in women’s sport must first address resource inequalities between men’s and women’s sport. This includes giving women access to quality training and coaching support, as well as <a href="https://theconversation.com/new-study-much-of-what-were-told-about-gym-exercises-and-resistance-training-is-from-studies-of-males-by-men-205753">greater attention</a> from sport science and medical research.</p> <p>The health of <a href="https://www.tandfonline.com/doi/full/10.1080/14443058.2019.1575262">women athletes and women’s sport</a> will only progress if researchers, policymakers and sport governance bodies ensure the attention and resources required to address concussion and brain disease are not focused solely on men.</p> <hr /> <p><em>If this article has raised issues for you, or if you’re concerned about someone you know, call <a href="https://www.lifeline.org.au/">Lifeline</a> on 13 11 14.<!-- Below is The Conversation's page counter tag. Please DO NOT REMOVE. --><img style="border: none !important; box-shadow: none !important; margin: 0 !important; max-height: 1px !important; max-width: 1px !important; min-height: 1px !important; min-width: 1px !important; opacity: 0 !important; outline: none !important; padding: 0 !important;" src="https://counter.theconversation.com/content/208929/count.gif?distributor=republish-lightbox-basic" alt="The Conversation" width="1" height="1" /><!-- End of code. If you don't see any code above, please get new code from the Advanced tab after you click the republish button. The page counter does not collect any personal data. More info: https://theconversation.com/republishing-guidelines --></em></p> <p><em><a href="https://theconversation.com/profiles/stephen-townsend-501829">Stephen Townsend</a>, Lecturer, School of Human Movement and Nutrition Sciences, <a href="https://theconversation.com/institutions/the-university-of-queensland-805">The University of Queensland</a>; <a href="https://theconversation.com/profiles/alan-pearce-734804">Alan Pearce</a>, Professor, College of Science, Health, Engineering, <a href="https://theconversation.com/institutions/la-trobe-university-842">La Trobe University</a>, and <a href="https://theconversation.com/profiles/rebecca-olive-944640">Rebecca Olive</a>, Vice Chancellor's Senior Research Fellow, <a href="https://theconversation.com/institutions/rmit-university-1063">RMIT University</a></em></p> <p><em>Image credits: Getty Images</em></p> <p><em>This article is republished from <a href="https://theconversation.com">The Conversation</a> under a Creative Commons license. Read the <a href="https://theconversation.com/australian-researchers-confirm-worlds-first-case-of-dementia-linked-to-repetitive-brain-trauma-in-a-female-athlete-208929">original article</a>.</em></p>

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Mum who gave birth during coma finally wakes

<p>A woman from the US has woken up from a coma to discover her baby had been born. </p> <p>Jackie Miller James, a 35-year-old beauty and lifestyle influencer, was found found unresponsive by her husband in June, after she suffered a brain aneurysm while heavily pregnant. </p> <p>Jackie fell into a coma following the traumatic event, with her sister posting a fundraiser to help her family through the difficult time. </p> <p>“We are deeply saddened to share that our sister, Jacqueline (Jackie), was nine months pregnant and one week from her due date, when she suffered an aneurysm rupture, leading to severe brain bleeding and injury,” she wrote. </p> <p>“Jackie was found immediately by her husband, Austin, and was rushed to the emergency room and into an operation where they performed an emergency C-section and brain surgery simultaneously.”</p> <p>In a heart-warming update, Jackie's family has confirmed that she is awake and has has an emotional reunion with her baby girl.</p> <blockquote class="instagram-media" style="background: #FFF; border: 0; border-radius: 3px; box-shadow: 0 0 1px 0 rgba(0,0,0,0.5),0 1px 10px 0 rgba(0,0,0,0.15); margin: 1px; max-width: 540px; min-width: 326px; padding: 0; width: calc(100% - 2px);" data-instgrm-permalink="https://www.instagram.com/p/CuNV3eDJP3-/?utm_source=ig_embed&amp;utm_campaign=loading" data-instgrm-version="14"> <div style="padding: 16px;"> <div style="display: flex; flex-direction: row; align-items: center;"> <div style="background-color: #f4f4f4; border-radius: 50%; flex-grow: 0; height: 40px; margin-right: 14px; width: 40px;"> </div> <div style="display: flex; flex-direction: column; flex-grow: 1; justify-content: center;"> <div style="background-color: #f4f4f4; border-radius: 4px; flex-grow: 0; height: 14px; margin-bottom: 6px; width: 100px;"> </div> <div style="background-color: #f4f4f4; border-radius: 4px; flex-grow: 0; height: 14px; width: 60px;"> </div> </div> </div> <div style="padding: 19% 0;"> </div> <div style="display: block; height: 50px; margin: 0 auto 12px; width: 50px;"> </div> <div style="padding-top: 8px;"> <div style="color: #3897f0; font-family: Arial,sans-serif; font-size: 14px; font-style: normal; font-weight: 550; line-height: 18px;">View this post on Instagram</div> </div> <div style="padding: 12.5% 0;"> </div> <div style="display: flex; flex-direction: row; margin-bottom: 14px; align-items: center;"> <div> <div style="background-color: #f4f4f4; border-radius: 50%; height: 12.5px; width: 12.5px; transform: translateX(0px) translateY(7px);"> </div> <div style="background-color: #f4f4f4; height: 12.5px; transform: rotate(-45deg) translateX(3px) translateY(1px); width: 12.5px; flex-grow: 0; margin-right: 14px; margin-left: 2px;"> </div> <div style="background-color: #f4f4f4; border-radius: 50%; height: 12.5px; width: 12.5px; transform: translateX(9px) translateY(-18px);"> </div> </div> <div style="margin-left: 8px;"> <div style="background-color: #f4f4f4; border-radius: 50%; flex-grow: 0; height: 20px; width: 20px;"> </div> <div style="width: 0; height: 0; border-top: 2px solid transparent; border-left: 6px solid #f4f4f4; border-bottom: 2px solid transparent; transform: translateX(16px) translateY(-4px) rotate(30deg);"> </div> </div> <div style="margin-left: auto;"> <div style="width: 0px; border-top: 8px solid #F4F4F4; border-right: 8px solid transparent; transform: translateY(16px);"> </div> <div style="background-color: #f4f4f4; flex-grow: 0; height: 12px; width: 16px; transform: translateY(-4px);"> </div> <div style="width: 0; height: 0; border-top: 8px solid #F4F4F4; border-left: 8px solid transparent; transform: translateY(-4px) translateX(8px);"> </div> </div> </div> <div style="display: flex; flex-direction: column; flex-grow: 1; justify-content: center; margin-bottom: 24px;"> <div style="background-color: #f4f4f4; border-radius: 4px; flex-grow: 0; height: 14px; margin-bottom: 6px; width: 224px;"> </div> <div style="background-color: #f4f4f4; border-radius: 4px; flex-grow: 0; height: 14px; width: 144px;"> </div> </div> <p style="color: #c9c8cd; font-family: Arial,sans-serif; font-size: 14px; line-height: 17px; margin-bottom: 0; margin-top: 8px; overflow: hidden; padding: 8px 0 7px; text-align: center; text-overflow: ellipsis; white-space: nowrap;"><a style="color: #c9c8cd; font-family: Arial,sans-serif; font-size: 14px; font-style: normal; font-weight: normal; line-height: 17px; text-decoration: none;" href="https://www.instagram.com/p/CuNV3eDJP3-/?utm_source=ig_embed&amp;utm_campaign=loading" target="_blank" rel="noopener">A post shared by Jackie Miller James (@jaxandrose)</a></p> </div> </blockquote> <p>The family shared that Jackie's recovery is exceeding expectations, with medical professionals pleased with her most recent tests. </p> <p>“The doctors have been pleased upon her latest tests, numbers and evaluations, noting that Jackie is performing above expectations at this stage of her recovery and is progressing more with every passing day,” the post read.</p> <p>“Jackie and Austin’s baby girl is a constant source of light for the entire family and continues to grow into a happy, healthy, and animated little angel."</p> <p>“Despite James’s delicate state of health, her daughter was delivered safely, spending 12 days in the NICU before going home.”</p> <p>Since Jackie's incident, a <a href="https://www.gofundme.com/f/support-jackies-long-road-to-recovery" target="_blank" rel="noopener">GoFundMe</a> campaign to support her and her family has amassed an incredible $500,000, as the funds will be allocated to cover the costs of Ms James’ speech therapy, physical therapy, necessary home modifications, and alternative therapies to address any lasting impairments she may face.</p> <p>Jackie's family thanked those who have donated for their support, writing, "The resources raised from the GoFundMe will allow us to continue to give Jackie the very best care and every chance at recovery. We are so appreciative of your donations, every little bit continues to help.”</p> <p><em>Image credits: GoFundMe</em></p>

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5 surprising factors damaging your heart

<p>It’s important to maintain heart health at all stages of life, but it becomes particularly crucial as we age – after all, the older you get, the older your heart becomes, too. And even though you might be taking all the right precautions (e.g. quitting smoking, eating a healthy diet, exercising regularly), you could be tarnishing your ticker without even realising it. Here are five things you didn’t know could negatively affect your heart health.</p> <p><strong>1. Damaged hearing</strong> – if you’ve spent much of your life working or living in noisy areas or regularly attending loud events (i.e. those rock concerts you frequented back in the day!), beware. A 2015 study found that people with high-frequency hearing loss in both years (most often due to prolonged exposure to high-decibel noise) were twice as prone to heart disease than those with normal hearing.</p> <p><strong>2. Air pollution</strong> – Have you been considering a sea or tree change? Now might be the time to do it. Researchers in 2011 discovered that exposure to traffic and air pollution is responsible for between 5 and 7 per cent of heart attacks around the world. Experts believe this may be due to an increase in arterial plaque build-up experienced by city-dwellers.</p> <p><strong>3. Sleep deprivation</strong> – A chronic lack of sleep increases production of adrenaline and cortisol (the stress hormone), which in turn increases your heart rate and blood pressure. In fact, one study found those who regularly had less than five hours of sleep were three times more at risk of heart attack than those who got between six and eight hours.</p> <p><strong>4. Excessive exercise</strong> – Believe it or not, but exercise could be putting you at risk of a heart attack – that is, if you’re doing too much vigorous exercise too often. Anything that causes strain can lead to dangerously high blood pressure – this means weightlifting and endurance sports (e.g. marathons) could be off the table. Stick to low-impact workouts like brisk walking, light weights and yoga.</p> <p><strong>5. Too much sitting</strong> – We’ve heard it all before – that sitting is bad for you – but you might not have realised just how bad it can be. According to a 2015 report, the average adult spends more than half of their waking hours sitting down, making them more likely to suffer or die from heart disease –even those who exercised an hour a day couldn’t combat this higher risk.</p> <p><em>Images: Getty</em></p>

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